Mesothelin (EP140) Rabbit Monoclonal Primary Antibody

SIGMA/439R-1

Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-439R-14	0.1 mL	$0.00 1/EA CALL FOR PRICE	Add To Favorites
45-439R-15	0.5 mL	$0.00 1/EA CALL FOR PRICE	Add To Favorites
45-439R-16	1 mL	$0.00 1/EA CALL FOR PRICE	Add To Favorites
45-439R-17	1 mL	$0.00 1/EA CALL FOR PRICE	Add To Favorites
45-439R-18	7 mL	$0.00 1/EA CALL FOR PRICE	Add To Favorites

Immunohistochemistry Mesothelin (EP140) on mesothelioma.

Properties
Descriptions
Safety Info.
Basic Data

antibody form	culture supernatant
antibody product type	primary antibodies
biological source	rabbit
clone	EP140, monoclonal
conjugate	unconjugated
description	(For In Vitro Diagnostic Use in Select Regions (See Chart))
form	buffered aqueous solution
isotype	IgG
manufacturer/tradename	Cell Marque^™
packaging	bottle of 1.0 mL predilute (439R-17)
	bottle of 7.0 mL predilute (439R-18)
	vial of 0.1 mL concentrate (439R-14)
	vial of 0.5 mL concentrate (439R-15)
	vial of 1.0 mL concentrate (439R-16)
Quality Level	100
	500
shipped in	wet ice
species reactivity	human
storage temp.	2-8°C
technique(s)	immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100

General description:

Mesothelin is a 40 kDa glycosyl-phosphatudylinositol-anchored glycoprotein cleaved from a 71kDa precursor protein encoded by the human mesothelin gene. Mesothelin is present on the surface of normal mesothelial cells.¹ Although the function of mesothelin is unknown, it is overexpressed in a wide variety of cancers including mesothelioma, pancreatic ductal adenocarcinoma, and ovarian carcinoma.^1-6 Mesothelin has proven to be a valuable marker for pancreatic ductal adenocarcinoma due to its strong reactivity in tumor tissue and absence in normal pancreas.^{1, 3-4} Metastatic renal cell carcinoma can present clinical patterns that mimic primary mesothelioma, pancreatic ductal adenocarcinoma, and ovarian carcinoma.^{2, 4-6} Mesothelin has demonstrated utility in the differential diagnosis between these primary tumors and corresponding metastatic renal cell carcinoma within the context of an antibody panel.^4-6

Legal Information:

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

Linkage:

Mesothelin Positive Control Slides, Product No. 439S External link

, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Other Notes:

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Physical form:

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Preparation Note:

Download the IFU specific to your product lot and format External link

Note: This requires a keycode which can be found on your packaging or product label.

Quality:

IVD

RUO

RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Storage Temp.	2-8°C
UNSPSC	12352200

To Order From a Quote