Erythromycin standard solution
SIGMA/45703 - 1 mg/mL in H2O
Synonym: Erythromycin from Streptomyces erythreus
CAS Number: 114-07-8
Empirical Formula (Hill Notation): C37H67NO13
Molecular Weight: 733.93
MDL Number: MFCD00084654
Linear Formula: C37H67NO13
Product Type: Chemical
| agency | EPA 1694 |
| antibiotic activity spectrum | Gram-positive bacteria |
| application(s) | environmental |
| biological source | Streptomyces erythreus (strains) |
| color | colorless |
| concentration | 1 mg/mL in H2O |
| form | liquid |
| InChI | 1S/C37H67NO13/c1-14-25-37 |
| InChI key | ULGZDMOVFRHVEP-RWJQBGPGSA |
| mode of action | protein synthesis | interferes |
| SMILES string | CC[C@H]1OC(=O)[C@H](C)C(O |
| storage temp. | 2-8°C |
| Application: | Erythromycin is an antibiotic produced by growth of certain strains of Streptomyces erythreus. This product is composed largely of erythromycin A with small amounts of erythromycins B and C and is recommended for concentration at 100 mg/L. Concentrations between 50 and 200 mg/L have also proven effective in controlling bacterial growth. Erythromycin has been used as a motilin receptor agonist, to block respiratory glycoconjugate secretion in human airways in vitro, and for selecting plasmid-cured and recombinant lactococcus lactis MG1363 strains. . |
| Biochem/physiol Actions: | Mode of Action: Erythromycin acts by inhibiting elongation at the transpeptidation step, specifically aminoacyl translocation from the A-site to P-site by binding to the 50s subunit of the bacterial 70s rRNA complex. Antimicrobial Spectrum: This product acts against both gram-negative and gram-positive bacteria. |
| Caution: | This Erythromycin solution is concentrated at 1 mg/mL in H2O and is stable in solution at 37°C for 3 days. Stock solutions should be stored at 2-8°C. |
| General description: | Chemical structure: macrolide |
| Other Notes: | Keep container tightly closed in a dry and well-ventilated place. Store under inert gas. |
| Packaging: | 10 ml |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| UNSPSC | 51101500 |