p57Kip2 (Kp10) Mouse Monoclonal Antibody
SIGMA/457M-9
Product Type: Chemical
antibody form | culture supernatant |
antibody product type | primary antibodies |
biological source | mouse |
clone | Kp10, monoclonal |
conjugate | unconjugated |
control | placenta |
description | For In Vitro Diagnostic Use in Select Regions (See Chart) |
form | buffered aqueous solution |
isotype | IgG2bκ |
manufacturer/tradename | Cell Marque™ |
packaging | bottle of 1.0 mL predilute (457M-97) |
bottle of 7.0 mL predilute (457M-98) | |
vial of 0.1 mL concentrate (457M-94) | |
vial of 0.5 mL concentrate (457M-95) | |
vial of 1.0 mL concentrate (457M-96) | |
Quality Level | 100 |
500 | |
shipped in | wet ice |
species reactivity | human |
storage temp. | 2-8°C |
technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500 |
visualization | nuclear |
General description: | Anti-p57 has been used as an aid in discriminating complete hydatidiform mole (CHM) (no nuclear labeling of cytotrophoblasts or stromal cells) from partial hydatidiform mole (PHM) (nuclear staining of both cytotrophoblasts and stromal cells) and hydropic abortion. In normal placenta, cytotrophoblast, syncytio trophoblast, and stromal cells are labeled with this antibody. Intervillous trophoblastic islands demonstrate nuclear labeling in all entities and serve as an internal control. | ||||
General description: | p57 is a human tumor suppressor gene encoded on the 11p15.5 chromosomal sequence. Anti-p57 has been used as an aid in discriminating complete hydatidiform mole (CHM) (no nuclear labeling of cytotrophoblasts or stromal cells) from partial hydatidiform mole (PHM) (nuclear staining of both cytotrophoblasts and stromal cells) and hydropic abortion. In the normal placenta, cytotrophoblast, intermediate trophoblast and decidual cells, and stromal cells are labeled with this antibody. Intervillous trophoblastic islands demonstrate nuclear labeling in all entities and serve as an internal control. | ||||
Legal Information: | Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany | ||||
Linkage: | P57Kip2 Positive Control Slides, Product No. 457S , are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections). | ||||
Other Notes: | For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com | ||||
Physical form: | Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide | ||||
Preparation Note: | Download the IFU specific to your product lot and format Note: This requires a keycode which can be found on your packaging or product label. | ||||
Quality: |
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RIDADR | NONH for all modes of transport |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |