Esterase from porcine liver
SIGMA/46058 - lyophilized, powder, slightly beige, ≥50 U/mg
Synonym: Carboxyl esterase; Carboxylic-ester hydrolase; PLE
CAS Number: 9016-18-6
EC Number: 232-773-7
MDL Number: MFCD00131030
Product Type: Chemical
| biological source | Porcine liver |
| color | slightly beige |
| form | lyophilized solid |
| powder | |
| mol wt | Mr ~162000 |
| quality | lyophilized |
| Quality Level | 100  |
| specific activity | ≥50 U/mg |
| storage temp. | −20°C |
| Application: | Esterase from porcine liver has been used as a negative control in fluorescence measurement studies. |
| Application: | Pig liver esterase is commonly used for kinetic resolutions and assymetric synthesis in organic chemistry. |
| Application: | Porcine liver esterase is used to catalyze the hydrolysis of pentaacetyl catechin and epicatechin for use in pharmaceutical and industrial applications. Pig liver esterase is commonly used for kinetic resolutions and assymetric synthesis in organic chemistry. |
| Biochem/physiol Actions: | Esterase acts on water-soluble carboxyl esters containing short chain fatty acids. Its functionality is attributed to the catalytic triad of Ser, His and Asp/Glu. |
| Biochem/physiol Actions: | Porcine liver esterase (PLE) displays good stability, broad substrate specificity, and is a low-cost enzyme. It is useful in the hydrolysis of ester- and amide-containing compounds, to free acids and is useful detoxification of xenobiotics. |
| Components: | contains 1,4-dithioerythritol |
| General description: | Porcine liver esterase (PLE) is localized in the endoplasmic reticulum (ER). |
| Other Notes: | Sales restrictions may apply |
| Unit Definition: | 1 U corresponds to the amount of enzyme which hydrolyzes 1 μmol ethyl valerate (CAt. No. 30784) per minute at pH 8.0 and 25°C |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| activity | specific activity: ≥50 U/mg |
| Storage Temp. | −20°C |
| Enzyme Commission (EC) Number | 3.1.1.1 ( BRENDA  | IUBMB ) |
| UNSPSC | 12352204 |