Fluorescein isothiocyanate–dextran
SIGMA/46944 - average mol wt 4,000, (FITC:Glucose = 1:250)
Synonym: FITC-Dextran 4; FITC–Dextran
CAS Number: 60842-46-8
MDL Number: MFCD00131092
Product Type: Chemical
| composition | (FITC:Glucose = 1:250) |
| extent of labeling | ~0.004 mol/mol FITC glucose |
| mol wt | average mol wt 4,000 |
| Quality Level | 100  |
| solubility | H2O: 50 mg/mL, slightly hazy, orange |
| storage temp. | 2-8°C |
| Application: | Dextran labeled with fluorescein isothiocyanate for possible use in perfusion studies in animals. |
| Application: | FITC-dextran is used extensively in microcirculation and cell permeability research utilizing microfluorimetry. FITC-dextran has been used to study plant cell wall porosity and capillary permeability. Plasma proteins have been shown not to bind to FITC-dextran. FITC-dextran is used in cardiovascular, microcirculation, perfusion, cell monolayer and cell membrane permeability research as fluorescent flux tracer compound that supports the measurement of processes such as blood flow, membrane damage, vascular drainage and renal elimination Fluorescein isothiocyanate–dextran (FITC-Dextran 4) is use as a fluorescent probe to study cell permeability. FITC-Dextran 4 is used with to study permeability of epithelial cell such as intestinal and renal cells in vivo. |
| Packaging: | Bottomless glass bottle. Contents are inside inserted fused cone. |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315 - H319 - H335 |
| Precautionary statements | P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352201 |