Fluorescein isothiocyanate–dextran
SIGMA/46946 - average mol wt 150,000, (FITC:Glucose = 1:160)
Synonym: FITC-Dextran 150; FITC–Dextran
CAS Number: 60842-46-8
MDL Number: MFCD00131092
Product Type: Chemical
| composition | (FITC:Glucose = 1:160) |
| extent of labeling | ~0.004 mol/mol FITC glucose |
| fluorescence | λex 492 nm; λem 518 nm in 0.1 M phosphate pH 8.0 |
| form | solid |
| mol wt | average mol wt 150,000 |
| Quality Level | 100  |
| solubility | H2O: 25 mg/mL, slightly hazy, very deep yellow-orange |
| storage temp. | 2-8°C |
| Application: | Dextran labeled with fluorescein isothiocyanate for possible use in perfusion studies in animals. |
| Application: | Fluorescein isothiocyanate–dextran (FITC-Dextran 150) is use as a fluorescent probe to study cell permeability. FITC-Dextran 150 is useful to study processes that affect the permeability of the blood brain barrier (BBB) and microvascular structures. FITC-Dextran 150 is used in fluorescence microlymphography. |
| Other Notes: | Commonly utilized as a macromolecular fluorochrome in inflammatory studies |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315 - H319 - H335 |
| Precautionary statements | P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C; 2-8°C |
| UNSPSC | 12352200 |