Saponin

SIGMA/47036 - for molecular biology, used as non-ionic surfactant

Synonym: Glycosides; Saponins

CAS Number: 8047-15-2
EC Number: 232-462-6
MDL Number: MFCD00081981
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-47036-50G-F	50 g	$112.00 1/EA		Add To Favorites
45-47036-250G-F	250 g	$459.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

CMC	0.001-0.01%
composition	Sapogenin, 8-25%
density	1.015-1.020 g/mL at 20 °C (5% in H₂O)(lit.)
foreign activity	DNase, RNase, Protease, Phosphatase, none detected
grade	for molecular biology
InChI	1S/C58H94O27/c1-52(2)29-7-11-55(5)30(8-12-58-31-15-53(3,22-62)13-14-57(31,23-77-58)32(64)16-56(55,58)6)54(29,4)10-9-33(52)82-50-46(85-51-45(40(71)37(68)27(19-61)80-51)84-49-43(74)39(70)36(67)26(18-60)79-49)44(83-48-42(73)38(69)35(66)25(17-59)78-48)28(21-76-50)81-47-41(72)34(65)24(63)20-75-47/h22,24-51,59-61,63-74H,7-21,23H2,1-6H3/t24-,25-,26-,27-,28+,29?,30-,31+,32-,33+,34+,35-,36-,37-,38+,39+,40+,41-,42-,43-,44+,45-,46-,47+,48-,49-,50+,51+,53-,54+,55-,56+,57?,58?/m1/s1
InChI key	MAEBCGDGGATMSC-OSHGGGOQSA-N
mol wt	1000-2000 g/mol
Quality Level	200
SMILES string	C[C@]1(CCC23COC4([C@H]2C1)CC[C@@H]5[C@]6(CC[C@@H](C(C6CC[C@]5([C@@]4(C[C@H]3O)C)C)(C)C)O[C@H]7[C@@H]([C@H]([C@H](CO7)O[C@H]8[C@@H]([C@H]([C@@H](CO8)O)O)O)O[C@@H]9[C@@H]([C@H]([C@@H]([C@H](O9)CO)O)O)O)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O[C@@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O)C)C=O
technique(s)	HPLC: suitable
	protein quantification: suitable

Application:	Glycoside used as a nonionic sufactant and adjuvant in vaccine development.
Application:	Saponin has been used: • in phosphate-buffered saline (PBS) to block cells for immunocytochemistry and confocal microscopy • to permeabilize cells for measuring total mitochondrial mass • as an internal control to extract saponin Holothuria nobilis Selenka
Biochem/physiol Actions:	Saponins are nonionic surfactant that forms oil-in-water emulsions and acts as a protective colloid. They are used for the direct determination of metals in milk by flame atomic absorption spectrophotometry.
Biochem/physiol Actions:	Saponins exhibit anti-tumor, antimicrobial, and anti-herbivore activity. They may also play a key role in plant defense. Saponins also possess several pharmaceutical properties, like anti-inflammatory, antifungal, antibacterial, anti-parasitic, and antiviral activities. Saponins can regulate rhizosphere bacteria in the soil.
General description:	Canonical SMILES: CC1(C2CCC3(C(C2(CCC1OC4C(C(C(CO4)OC5C(C(C(CO5)O)O)O)OC6C(C(C(C(O6)CO)O)O)O)OC7C(C(C(C(O7)CO)O)O)OC8C(C(C(C(O8)CO)O)O)O)C)CCC91C3(CC(C2(C9CC(CC2)(C)C=O)CO1)O)C)C)C
General description:	Saponins are a large family of amphiphilic glycosides of steroids and triterpenes. Saponins are found in many plants and are localized especially in the root, tuber, bark, leaves, seed, and fruit. They are also present in some animals, like sea cucumber.

Symbol	GHS07
Signal word	Warning
Hazard statements	H319 - H335
Precautionary statements	P261 - P264 - P271 - P280 - P304 + P340 + P312 - P305 + P351 + P338
Hazard Codes	Xi
Risk Statements	36/37
Safety Statements	26-37/39
RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Density	1.015-1.020 g/mL at 20 °C (5% in H₂O)(lit.)
UNSPSC	12161900

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