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N-Formyl-Met-Leu-Phe

SIGMA/47729 - BioXtra, ≥99.0% (TLC)

Synonym: Chemotactic peptide; N-Formyl-L-methionyl-L-leucyl-L-phenylalanine; fMLF; fMLP (misnomer but widely used)

CAS Number: 59880-97-6
Empirical Formula (Hill Notation): C21H31N3O5S
Molecular Weight: 437.55
MDL Number: MFCD00036780
Linear Formula: C21H31N3O5S
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-47729-10MG-F 10 mg
 $170.00
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application(s) cell analysis
assay ≥99.0% (TLC)
color white
form powder
InChI 1S/C21H31N3O5S/c1-14(2)11-17(23-19(26)16(22-13-25)9-10-30-3)20(27)24-18(21(28)29)12-15-7-5-4-6-8-15/h4-8,13-14,16-18H,9-12H2,1-3H3,(H,22,25)(H,23,26)(H,24,27)(H,28,29)/t16-,17-,18-/m0/s1
InChI key PRQROPMIIGLWRP-BZSNNMDCSA-N
product line BioXtra
Quality Level 100 
SMILES string CSCC[C@H](NC=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(O)=O
solubility DMF: 50 mg/mL, clear, colorless
storage temp. 2-8°C
Amino Acid Sequence: NFor-Met-Leu-Phe
Application: 1. 4th and 5th applications do not have access
2. 3rd application is not relevant
Biochem/physiol Actions: N-Formyl-Met-Leu-Phe is a potent chemotactic peptide and formyl peptide receptor (FPR) agonist that induces a metabolic burst in macrophages accompanied by an increase in respiratory rate, secretion of lysosomal enzymes, and production of superoxide anion.
Biochem/physiol Actions: Potent chemotactic peptide. Induces a metabolic burst in macrophages accompanied by an increase in respiratory rate, secretion of lysosomal enzymes, and production of superoxide anion.
Packaging: Bottomless glass bottle. Contents are inside inserted fused cone.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥99.0% (TLC)
Storage Temp. 2-8°C
UNSPSC 12352209

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