Glycine
SIGMA/50046 - BioUltra, Molecular Biology, ≥99.0% (NT)
Synonym: Aminoacetic acid; Aminoethanoic acid; Glycocoll
CAS Number: 56-40-6
Empirical Formula (Hill Notation): C2H5NO2
Molecular Weight: 75.07
EC Number: 200-272-2
MDL Number: MFCD00008131
Linear Formula: NH2CH2COOH
Product Type: Chemical
| λ | 1 M in 1 M HCl |
| anion traces | chloride (Cl-): ≤50 mg/kg |
| sulfate (SO42-): ≤100 mg/kg | |
| assay | ≥99.0% (NT) |
| cation traces | Al: ≤5 mg/kg |
| As: ≤0.1 mg/kg | |
| Ba: ≤5 mg/kg | |
| Bi: ≤5 mg/kg | |
| Ca: ≤10 mg/kg | |
| Cd: ≤5 mg/kg | |
| Co: ≤5 mg/kg | |
| Cr: ≤5 mg/kg | |
| Cu: ≤5 mg/kg | |
| Fe: ≤5 mg/kg | |
| K: ≤50 mg/kg | |
| Li: ≤5 mg/kg | |
| Mg: ≤5 mg/kg | |
| Mn: ≤5 mg/kg | |
| Mo: ≤5 mg/kg | |
| Na: ≤100 mg/kg | |
| NH4+: ≤200 mg/kg | |
| Ni: ≤5 mg/kg | |
| Pb: ≤5 mg/kg | |
| Sr: ≤5 mg/kg | |
| Zn: ≤5 mg/kg | |
| color | white |
| form | crystalline |
| grade | Molecular Biology |
| ign. residue | ≤0.05% (as SO4) |
| impurities | DNases, none detected |
| insoluble matter, passes filter test | |
| phosphatases, none detected | |
| proteases, none detected | |
| RNases, none detected | |
| InChI | 1S/C2H5NO2/c3-1-2(4)5/h1, |
| InChI key | DHMQDGOQFOQNFH-UHFFFAOYSA |
| loss | ≤0.05% loss on drying, HV, 20-26 °C |
| mp | 240 °C (dec.) (lit.) |
| pKa (25 °C) | (1) 2.35, (2) 9.60 |
| 2.35 | |
| product line | BioUltra |
| Quality Level | 200 ![]() |
| SMILES string | NCC(O)=O |
| solubility | 1 M HCl: 1 M at 20 °C, clear, colorless |
| UV absorption | λ: 260 nm Amax: 0.05 |
| λ: 280 nm Amax: 0.05 |
| Application: | Glycine has been used as a component of the viral extraction mixture for adenovirus viral extraction. |
| Biochem/physiol Actions: | Glycine is a non-essential amino acid. It is involved in the synthesis of purines, serine and porphyrins. Glycine-gated channels mediate the influx of calcium through cell membranes. It also acts as a competitive agonist for glutamate in binding to the NMDA (N-methyl-D-aspartate) receptors. In cancer cells, the synthesis of glycine might be increased due to increased demand for the amino acid. |
| Biochem/physiol Actions: | Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors. |
| Packaging: | 1 kg in poly bottle |
| Packaging: | 50, 250 g in poly bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥99.0% (NT) |
| mp | 240 °C (dec.) (lit.) |
| UNSPSC | 12352209 |

