Glyoxal solution
SIGMA/50649 - for molecular biology, BioReagent, ~40% in H2O (~8.8 M)
Synonym: Ethanedial; Oxalaldehyde
CAS Number: 107-22-2
Empirical Formula (Hill Notation): C2H2O2
Molecular Weight: 58.04
MDL Number: MFCD00006957
Linear Formula: OHCCHO
Product Type: Chemical
| anion traces | chloride (Cl-): ≤100 mg/kg |
| sulfate (SO42-): ≤100 mg/kg | |
| cation traces | Ca: ≤5 mg/kg |
| Cd: ≤5 mg/kg | |
| Co: ≤5 mg/kg | |
| Cr: ≤5 mg/kg | |
| Cu: ≤5 mg/kg | |
| Fe: ≤5 mg/kg | |
| K: ≤5 mg/kg | |
| Mg: ≤5 mg/kg | |
| Mn: ≤5 mg/kg | |
| Na: ≤300 mg/kg | |
| Ni: ≤5 mg/kg | |
| Pb: ≤5 mg/kg | |
| Zn: ≤5 mg/kg | |
| concentration | ~40% in H2O (~8.8 M) |
| form | liquid |
| grade | for molecular biology |
| impurities | DNases, none detected |
| phosphatases, none detected | |
| proteases, none detected | |
| RNases, none detected | |
| InChI | 1S/C2H2O2/c3-1-2-4/h1-2H |
| InChI key | LEQAOMBKQFMDFZ-UHFFFAOYSA |
| product line | BioReagent |
| Quality Level | 100  |
| refractive index | n |
| SMILES string | [H]C(=O)C([H])=O |
| storage temp. | 2-8°C |
| Application: | Suitable for • nucleic acid denaturation • binding of DNA/RNA to nitrocellulose membrane |
| Caution: | May precipitate on storage; redissolve at 50-60 °C. |
| General description: | Glyoxal is a nucleic acid denaturant. It acts as a specific probe for homopurine strands of DNA. |
| Other Notes: | May precipitate on storage; redissolve at 50-60 °C. |
| Other Notes: | This form of glyoxal is composed of 3 moles of glyoxal and 2 moles of water in a relatively stable configuration. |
| Principle: | Glyoxal forms stable complex with guanine residues that results in denaturation of nucleic acids. |
| Symbol |   GHS07,GHS08 |
| Signal word | Warning |
| Hazard statements | H315 - H317 - H319 - H332 - H341 |
| Precautionary statements | P201 - P280 - P302 + P352 - P304 + P340 + P312 - P305 + P351 + P338 - P308 + P313 |
| Hazard Codes | Xn |
| Risk Statements | 20-36/38-43-68 |
| Safety Statements | 36/37 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Refractive Index | n |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352114 |