Gramicidin C from Bacillus brevis
SIGMA/50847 - ~90% (HPLC)
CAS Number: 9062-61-7
Product Type: Chemical
antibiotic activity spectrum | Gram-negative bacteria |
Gram-positive bacteria | |
assay | ~90% (HPLC) |
biological source | Bacillus brevis |
color | white to off-white |
form | powder |
impurities | ≤5% water |
mode of action | cell membrane | interferes |
enzyme | inhibits | |
Quality Level | 100 |
SMILES string | CC(C)C[C@@H]1NC(=O)[C@H]( |
storage temp. | 2-8°C |
Application: | Gramicidin is a naturally occuring polypeptide antibiotic. It functions as a transmembrane ion channel and is used for studies on phospholipid bilayer membrane fluidity measured by lateral diffusion. |
Biochem/physiol Actions: | Gramicidin′s bactericidal activity is a result of increasing the permeability of the bacterial cell membrane. This allows inorganic monovalent cations to travel through unrestricted which thereby destroys the ion gradient between the cytoplasm and the extracellular environment . |
Biochem/physiol Actions: | Naturally occuring polypeptide antibiotic with Tyr at position 11; functions as a transmembrane ion channel. |
General description: | Chemical structure: peptide |
Other Notes: | Keep container tightly closed in a dry and well-ventilated place.Keep in a dry place. Keep in a dry place. |
Packaging: | 10mg |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ~90% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 51101500 |