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Gramicidin C from Bacillus brevis

SIGMA/50847 - ~90% (HPLC)

CAS Number: 9062-61-7
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-50847-10MG 10 mg
$217.00
1/EA
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antibiotic activity spectrum Gram-negative bacteria
  Gram-positive bacteria
assay ~90% (HPLC)
biological source Bacillus brevis
color white to off-white
form powder
impurities ≤5% water
mode of action cell membrane | interferes
  enzyme | inhibits
Quality Level 100 
SMILES string CC(C)C[C@@H]1NC(=O)[C@H](CCCN)NC(=O)[C@@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCN)NC(=O)[C@@H](NC(=O)[C@@H]4CCCN4C(=O)[C@@H](Cc5ccccc5)NC1=O)C(C)C)C(C)C
storage temp. 2-8°C
Application: Gramicidin is a naturally occuring polypeptide antibiotic. It functions as a transmembrane ion channel and is used for studies on phospholipid bilayer membrane fluidity measured by lateral diffusion.
Biochem/physiol Actions: Gramicidin′s bactericidal activity is a result of increasing the permeability of the bacterial cell membrane. This allows inorganic monovalent cations to travel through unrestricted which thereby destroys the ion gradient between the cytoplasm and the extracellular environment .
Biochem/physiol Actions: Naturally occuring polypeptide antibiotic with Tyr at position 11; functions as a transmembrane ion channel.
General description: Chemical structure: peptide
Other Notes: Keep container tightly closed in a dry and well-ventilated place.Keep in a dry place. Keep in a dry place.
Packaging: 10mg
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ~90% (HPLC)
Storage Temp. 2-8°C
UNSPSC 51101500

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