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L-Histidine dihydrochloride

SIGMA/53340 - ≥99.0% (AT)

Synonym: L-Histidine hydrochloride (1:2)

CAS Number: 6027-02-7
Empirical Formula (Hill Notation): C6H9N3O2 · 2HCl
Molecular Weight: 228.08
EC Number: 227-890-5
MDL Number: MFCD00066569
Linear Formula: C6H9N3O2 · 2HCl
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-53340-10G 10 g
$183.00
1/EA
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45-53340-50G 50 g
$670.00
1/EA
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anion traces sulfate (SO42-): ≤50 mg/kg
assay ≥99.0% (AT)
cation traces As: ≤0.1 mg/kg
  Cd: ≤5 mg/kg
  Co: ≤5 mg/kg
  Cu: ≤5 mg/kg
  Fe: ≤5 mg/kg
  NH4+: ≤500 mg/kg
  Ni: ≤5 mg/kg
  Pb: ≤5 mg/kg
  Zn: ≤5 mg/kg
color white
form powder or crystals
ign. residue ≤0.1% (as SO4)
InChI 1S/C6H9N3O2.2ClH/c7-5(6(10)11)1-4-2-8-3-9-4;;/h2-3,5H,1,7H2,(H,8,9)(H,10,11);2*1H/t5-;;/m0../s1
InChI key XEJCDBUNISUVGZ-XRIGFGBMSA-N
mp 240-245 °C (dec.)
optical activity [α]20/D +6.5±1°, c = 8% in H2O
Quality Level 100 
SMILES string Cl.Cl.N[C@@H](Cc1c[nH]cn1)C(O)=O
solubility H2O: soluble
  saline: soluble
Biochem/physiol Actions: L-Histidine is a natural proteinogenic α amino acid useful as a cell growth supplement that support protein and peptide biosynthesis. L-Histidine is studied in a wide range of applications that involve imidazole chemistry and biochemisty.
Biochem/physiol Actions: L-Histidine is a positively charged imidazole-side chain containing α amino acid. It is metabolized to histamine and is a precursor of the dipeptide carnosine. As one of the 22 proteinogenic amino acids L-His is incorporated into proteins by translation processes in vitro. L-Histidine is an essential amino acid added to cell culture media.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥99.0% (AT)
mp 240-245 °C (dec.)
UNSPSC 12352209

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