Human Lung Microvascular Endothelial Cells: HLMVEC, adult
SIGMA/540-05A
Synonym: HLMVEC; HLMVEC cells
Product Type: Product-on-demand
Cell Applications : (A) HLMVEC in culture; (B) HLMVEC immunolabeled for CD31/PECAM (green); nuclei are visualized with PI (red); (C, D) HLMVEC transfected with GFP plasmid DNA.
| biological source | human lung (normal) |
| growth mode | Adherent |
| karyotype | 2n = 46 |
| manufacturer/tradename | Cell Applications, Inc |
| morphology | Endothelial |
| packaging | pkg of 500,000 cells |
| Quality Level | 100  |
| relevant disease(s) | metastasis |
| shipped in | dry ice |
| storage temp. | −196°C |
| technique(s) | cell culture | mammalian: suitable |
| Application: | lung physiology, metabolism, regulate blood composition, hemostasis, immune reactions, therapeutic effects, leukocyte migration, |
| Cell Line Origin: | Lungs |
| Components: | Cell Basal Medium containing 10% FBS & 10% DMSO |
| Disclaimer: | RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization. |
| General description: | Lot specific orders are not able to be placed through the web. Contact your local sales rep for more details. The pulmonary vasculature is of great physiological/pathologica HLMVEC have been used to elucidate the therapeutic effects of Angiotensin I-converting enzyme (ACE) inhibitors, and the results revealed that they provide an additional benefit to patients by activating bradykinin B1 receptor leading to prolonged nitric oxide (NO) production in endothelial cells and inhibition of PKCε (Ignjatovic, 2004; Stanisavljevic, 2006). |
| Preparation Note: | • 3rd passage, >500,000 cells in Cell Basal Medium containing 10% FBS & 10% DMSO • Can be cultured at least 15 doublings |
| Subculture Routine: | Please refer to the HLMVEC Culture Protocol . |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −196°C |
| UNSPSC | 41106514 |