Sodium iodoacetate
SIGMA/57858 - BioUltra, ≥99.5% (NT)
Synonym: Iodoacetic acid sodium salt
CAS Number: 305-53-3
Empirical Formula (Hill Notation): C2H2INaO2
Molecular Weight: 207.93
EC Number: 206-165-7
MDL Number: MFCD00002686
Linear Formula: ICH2COONa
Product Type: Chemical
absorption | cut-off at 335 nm in methanol at 0.1 M |
anion traces | chloride (Cl-): ≤100 mg/kg |
sulfate (SO42-): ≤100 mg/kg | |
assay | ≥99.5% (NT) |
cation traces | Al: ≤5 mg/kg |
As: ≤0.1 mg/kg | |
Ba: ≤5 mg/kg | |
Bi: ≤5 mg/kg | |
Ca: ≤10 mg/kg | |
Cd: ≤5 mg/kg | |
Co: ≤5 mg/kg | |
Cr: ≤5 mg/kg | |
Cu: ≤5 mg/kg | |
Fe: ≤5 mg/kg | |
K: ≤500 mg/kg | |
Li: ≤5 mg/kg | |
Mg: ≤5 mg/kg | |
Mn: ≤5 mg/kg | |
Mo: ≤5 mg/kg | |
Ni: ≤5 mg/kg | |
Pb: ≤5 mg/kg | |
Sr: ≤5 mg/kg | |
Zn: ≤5 mg/kg | |
impurities | insoluble matter, passes filter test |
≤0.5% water | |
InChI | 1S/C2H3IO2.Na/c3-1-2(4)5; |
InChI key | AGDSCTQQXMDDCV-UHFFFAOYSA |
mp | 208 °C (dec.) (lit.) |
product line | BioUltra |
Quality Level | 100 |
SMILES string | [Na+].[O-]C(=O)CI |
solubility | methanol: 0.1 M at 20 °C, clear, colorless |
storage temp. | −20°C |
Application: | Reagent for the modification of cysteine residues in proteins. Used in protein sequencing (including by Sanger in sequencing bovine insulin) to prevent oxidation of -SH sidechains. |
Application: | Reagent for the modification of cysteine residues in proteins. Used to induce animal osteoarthritis model system, which mimics both symptoms and histopathology of the human disease. |
Other Notes: | Sulfhydryl reagent |
Symbol | GHS05,GHS06 |
Signal word | Danger |
Hazard statements | H301 - H314 |
Precautionary statements | P260 - P270 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 |
Hazard Codes | T |
Risk Statements | 25-37/38-41 |
Safety Statements | 26-39-45 |
RIDADR | UN 2811 6.1 / PGIII |
WGK Germany | WGK 3 |
Flash Point(F) | 406.4 °F |
Flash Point(C) | 208 °C |
Purity | ≥99.5% (NT) |
mp | 208 °C (dec.) (lit.) |
Storage Temp. | −20°C |
UNSPSC | 12352106 |