Iodonitrotetrazolium chloride
SIGMA/58030 - BioReagent, ≥97.0% (calc. on dry substance, NT)
Synonym: 2-
CAS Number: 146-68-9
Empirical Formula (Hill Notation): C19H13ClIN5O2
Molecular Weight: 505.70
EC Number: 205-676-2
MDL Number: MFCD00011961
Linear Formula: C19H13ClIN5O2
Product Type: Chemical
application(s) | histology |
assay | ≥97.0% (calc. on dry substance, NT) |
InChI | 1S/C19H13IN5O2.ClH/c20-15 |
InChI key | JORABGDXCIBAFL-UHFFFAOYSA |
mp | 240 °C (dec.) (lit.) |
~245 °C (dec.) | |
product line | BioReagent |
Quality Level | 200 |
SMILES string | [Cl-].[O-][N+](=O)c1ccc(c |
solubility | methanol: water (1:1): 50 mg/mL, very faintly turbid, very deep yellow (hot) |
Application: | Electron acceptor for the colorimetric assay of various dehydrogenases |
Application: | Iodonitrotetrazolium (INT) is a tetrazolium dye precursor that forms a purple formazan dye on reduction and has been used in a variety of applications. It is considered to have higher reactivity than some tetrazolium compounds, at least with respect to succinate dehydrogenase, with optimal results obtained using a concentration of 0.8 mM INT. INT is used as an electron acceptor for the colorimetric assays of: lactate dehydrogenase, xanthine dehydrogenase, lactyl-CoA dehydrogenase, succinate dehydrogenase, BBM II ketolisomerase, histidinol dehydrogenase and diverse other hydrolases. |
Symbol | GHS02,GHS07 |
Signal word | Danger |
Hazard statements | H228 - H335 |
Precautionary statements | P210 - P240 - P241 - P261 - P271 - P280 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Purity | ≥97.0% (calc. on dry substance, NT) |
mp | 240 °C (dec.) (lit.); ~245 °C (dec.) |
UNSPSC | 12352102 |