Betaine
SIGMA/61962 - BioUltra, ≥99.0% (NT)
Synonym: (Carboxymethyl)
CAS Number: 107-43-7
Empirical Formula (Hill Notation): C5H11NO2
Molecular Weight: 117.15
EC Number: 203-490-6
MDL Number: MFCD00012123
Linear Formula: (CH3)3N+CH2COO-
Product Type: Chemical
| absorption | ≤0.05 at 280 nm in methanol at 1 M |
| ≤0.09 at 260 nm in methanol at 1 M | |
| anion traces | chloride (Cl-): ≤200 mg/kg |
| sulfate (SO42-): ≤200 mg/kg | |
| assay | ≥99.0% (NT) |
| cation traces | Ca: ≤10 mg/kg |
| Cd: ≤5 mg/kg | |
| Co: ≤5 mg/kg | |
| Cr: ≤5 mg/kg | |
| Cu: ≤5 mg/kg | |
| Fe: ≤5 mg/kg | |
| K: ≤50 mg/kg | |
| Mg: ≤5 mg/kg | |
| Mn: ≤5 mg/kg | |
| Na: ≤100 mg/kg | |
| Ni: ≤5 mg/kg | |
| Pb: ≤5 mg/kg | |
| Zn: ≤5 mg/kg | |
| impurities | insoluble matters, passes filter test |
| InChI | 1S/C5H11NO2/c1-6(2,3)4-5( |
| InChI key | KWIUHFFTVRNATP-UHFFFAOYSA |
| product line | BioUltra |
| Quality Level | 200  |
| SMILES string | C[N+](C)(C)CC([O-])=O |
| solubility | methanol: 1 M at 20 °C, clear, colorless |
| Application: | Betaine has been used in reverse transcription to increase the thermal stability of proteins and to destabilize the DNA helix. |
| Biochem/physiol Actions: | Betaine has been shown to increase S-adenosylmethionine (SAM) levels and hence, may have a role in diminishing hepatic steatosis. It is an osmolyte which protects cells against environmental stress. |
| Biochem/physiol Actions: | End-product of oxidative metabolism of choline, betaine is a general methyl donor, in particular in a minor pathway of methionine biosynthesis. It is used to treat homocystinuria, which is a defect in the major pathway of methionine biosynthesis. |
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| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥99.0% (NT) |
| UNSPSC | 12352200 |