L-Methionine
SIGMA/64319 - BioUltra, ≥99.5% (NT)
Synonym: (S)
CAS Number: 63-68-3
Empirical Formula (Hill Notation): C5H11NO2S
Molecular Weight: 149.21
EC Number: 200-562-9
MDL Number: MFCD00063097
Linear Formula: CH3SCH2CH2CH(NH2)CO2H
Product Type: Chemical
| λ | 0.5 M in 1 M HCl |
| anion traces | chloride (Cl-): ≤50 mg/kg |
| sulfate (SO42-): ≤100 mg/kg | |
| assay | ≥99.5% (NT) |
| biological source | synthetic |
| cation traces | Al: ≤5 mg/kg |
| As: ≤0.1 mg/kg | |
| Ba: ≤5 mg/kg | |
| Bi: ≤5 mg/kg | |
| Ca: ≤10 mg/kg | |
| Cd: ≤5 mg/kg | |
| Co: ≤5 mg/kg | |
| Cr: ≤5 mg/kg | |
| Cu: ≤5 mg/kg | |
| Fe: ≤5 mg/kg | |
| K: ≤50 mg/kg | |
| Li: ≤5 mg/kg | |
| Mg: ≤5 mg/kg | |
| Mn: ≤5 mg/kg | |
| Mo: ≤5 mg/kg | |
| Na: ≤50 mg/kg | |
| NH4+: ≤100 mg/kg | |
| Ni: ≤5 mg/kg | |
| Pb: ≤5 mg/kg | |
| Sr: ≤5 mg/kg | |
| Zn: ≤5 mg/kg | |
| color | white |
| form | powder or crystals |
| ign. residue | ≤0.1% |
| impurities | insoluble matter, passes filter test |
| ≤0.5% foreign amino acids | |
| InChI | 1S/C5H11NO2S/c1-9-3-2-4(6 |
| InChI key | FFEARJCKVFRZRR-BYPYZUCNSA |
| loss | ≤0.1% loss on drying, 20 °C (HV) |
| mp | 284 °C (dec.) (lit.) |
| optical activity | [α]20/D +23.7±0.5°, c = 5% in 5 M HCl |
| product line | BioUltra |
| Quality Level | 200  |
| SMILES string | CSCC[C@H](N)C(O)=O |
| solubility | 1 M HCl: 0.5 M at 20 °C, clear, colorless |
| UV absorption | λ: 260 nm Amax: 0.40 |
| λ: 280 nm Amax: 0.05 |
| Application: | <ul><BR/><li><strong>ROS-Responsiv<WBR>e and Self-Tumor Curing Methionine Polymer Library Based Nanoparticles with Self-Accelerated Drug Release and Hydrophobicity/Hydrophili<WBR>city Switching Capability for Enhanced Cancer Therapy</strong>: This publication details the development of L-Methionine based nanoparticles, showcasing its pivotal role in advancing drug delivery systems for cancer treatment. The study highlights the potential of these systems in enhancing therapeutic efficacy through controlled drug release (<A class="External" onClick="cmCreateManualPageviewTag('doi.org - 64319 SIGMA', 'EXTERNAL LINKS', 'https://doi.org/10.1002/smll.202401438', window.location);" rel="nofollow" href="https://doi.org/10.1002/smll.202401438">Liu et al., 2024</A><img src="https://krackeler.com/images/pixel.png">).</li><BR/><li><strong>N-acetyl-l-me<WBR>thionine dietary supplementation improves meat quality by oxidative stability of finishing Angus heifers</strong>: This study explores the benefits of L-Methionine supplementation in animal diets, emphasizing its impact on improving meat quality and oxidative stability, which is crucial for the meat production industry and nutritional science (<A class="External" onClick="cmCreateManualPageviewTag('doi.org - 64319 SIGMA', 'EXTERNAL LINKS', 'https://doi.org/10.1016/j.meatsci.2024.109499', window.location);" rel="nofollow" href="https://doi.org/10.1016/j.meatsci.2024.109499">Liu et al., 2024</A><img src="https://krackeler.com/images/pixel.png">).</li><BR/></ul><BR/> |
| Other Notes: | Synthesis of labels for protonation studies by Fourier Transform Infrared Methods for L-glutaric-513C acid; Spacer in isotachophoresis of serum proteins; Essential in culture media for some malignant human cell lines; Growth requirement of various microorganisms |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥99.5% (NT) |
| mp | 284 °C (dec.) (lit.) |
| UNSPSC | 12352209 |