Tris(2-carboxyethyl)phosphine hydrochloride

SIGMA/68957 - BioUltra, suitable for electrophoresis, SDS-PAGE tested

Synonym: TCEP.HCL; TCEP

CAS Number: 51805-45-9
Empirical Formula (Hill Notation): C₉H₁₅O₆P · HCl
Molecular Weight: 286.65
MDL Number: MFCD00145469
Linear Formula: C₉H₁₅O₆P · HCl
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-68957-10G	10 g	$1110.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	97.5-102.5%
form	powder
InChI	1S/C9H15O6P.ClH/c10-7(11)1-4-16(5-2-8(12)13)6-3-9(14)15;/h1-6H2,(H,10,11)(H,12,13)(H,14,15);1H
InChI key	PBVAJRFEEOIAGW-UHFFFAOYSA-N
product line	BioUltra
Quality Level	100
SMILES string	Cl[H].OC(=O)CCP(CCC(O)=O)CCC(O)=O
solubility	H₂O: soluble
suitability	SDS-PAGE tested
technique(s)	electrophoresis: suitable

Analysis Note:	agarose gel electrophorese corresponds to requirements
Application:	TCEP.HCL has been used in various bioconjugation applications, both in vitro and in vivo, to tag proteins and live organisms with great effectiveness under mild physiological circumstances. TCEP.HCL is suitable for varied biological and synthetic applications. At an acidic pH, TCEP.HCL can be used to convert organic disulfides to thiols in water irreversibly.
Application:	Water soluble reagent, used for selective reduction of disulfides. More stable than DTT and useful in mass spectrometry applications.
Features and Benefits:	The product has the following benefits: • TCEP.HCL lowers reactive oxygen species levels. • It increases glutathione levels and mitochondrial content. • It has anti-cancer effects.
General description:	Tris(2-carboxyethyl) phosphine hydrochloride (TCEP.HCL ) is a useful reducing agent for Sulphur and nitrogen-containing compounds. TCEP.HCL and the resultant oxide are water-soluble. TCEP.HCL has electron-rich phosphorus and oxygen atoms to combine with various metals, including Rh, Ir, and Pd. It rapidly complexes with Rh and Ir in dioxane at ambient temperature. It reduces disulfide linkages in a range of peptides and proteins in biological disulfide.

Symbol	GHS05
Signal word	Danger
Hazard statements	H314
Precautionary statements	P260 - P280 - P301 + P330 + P331 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
Hazard Codes	C
Risk Statements	34
Safety Statements	26-27-36/37/39
RIDADR	UN 3261 8 / PGII
WGK Germany	WGK 1

Purity	97.5-102.5%
UNSPSC	12352128

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