L-Homocysteine
SIGMA/69453 - ≥98.0% (NT)
Synonym: (S)
CAS Number: 6027-13-0
Empirical Formula (Hill Notation): C4H9NO2S
Molecular Weight: 135.18
EC Number: 227-891-0
MDL Number: MFCD00151320
Linear Formula: HSCH2CH2CH(NH2)COOH
Product Type: Chemical
application(s) | cell analysis |
assay | ≥98.0% (NT) |
color | white |
form | powder |
InChI | 1S/C4H9NO2S/c5-3(1-2-8)4( |
InChI key | FFFHZYDWPBMWHY-VKHMYHEASA |
mp | 263-265 °C |
optical activity | [α]/D 25.5±1.5°, c = 1 in 1 M HCl |
Quality Level | 100 |
relevant disease(s) | Alzheimer′s disease |
SMILES string | N[C@@H](CCS)C(O)=O |
storage temp. | −20°C |
Application: | |
Biochem/physiol Actions: | Elevated homocysteine levels in plasma and tissue are associated with brain atrophy in Alzheimer′s disease as well as in healthy eldery subjects. Increased homocysteine is due to deficiencies in vitamin B status, specifically folate, B6 and B12 vitamins, which act as cofactors for enzymes involved in homocysteine metabolism. |
General description: | |
Packaging: | Bottomless glass bottle. Contents are inside inserted fused cone. |
Symbol | GHS07 |
Signal word | Warning |
Hazard statements | H302 |
Hazard Codes | Xn |
Risk Statements | 22 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98.0% (NT) |
mp | 263-265 °C |
Storage Temp. | −20°C |
UNSPSC | 12352204 |