Naphthol Yellow S

SIGMA/70540 - suitable for microscopy

Synonym: 2,4-Dinitro-1-naphthol-7-sulfonic acid sodium salt; 5,7-Dinitro-8-hydroxy-2-naphthalenesulfonic acid sodium salt; Acid Yellow 1; Flavianic acid sodium salt

CAS Number: 846-70-8
Empirical Formula (Hill Notation): C₁₀H₄N₂Na₂O₈S
Molecular Weight: 358.19
EC Number: 212-690-2
MDL Number: MFCD00003958
Linear Formula: C₁₀H₄N₂Na₂O₈S
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-70540-25G	25 g	$37.80 1/EA	Add To Favorites
45-70540-100G	100 g	$120.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

ε_max	≥275 at 423-433 nm in water
	≥≥ 250 at 387-397 nm in water
application(s)	diagnostic assay manufacturing hematology histology
form	powder
InChI	1S/C10H6N2O8S.2Na/c13-10-7-3-5(21(18,19)20)1-2-6(7)8(11(14)15)4-9(10)12(16)17;;/h1-4,13H,(H,18,19,20);;/q;2*+1/p-2
InChI key	CTIQLGJVGNGFEW-UHFFFAOYSA-L
Quality Level	200
SMILES string	[Na+].[Na+].[O-]c1c(cc([N+]([O-])=O)c2ccc(cc12)S([O-])(=O)=O)[N+]([O-])=O
solubility	methanol: water (1:1): 0.5 g/10 mL, clear
storage temp.	room temp
suitability	suitable for microscopy

Analysis Note:	λ_max. ∼428 nm/∼392 nm; E(1%,1 cm) ∼275-425/∼250-400 (H₂O)
Application:	Naphthol yellow S has been used as a staining agent in fixed human embryonic stem cell-derived cardiomyocytes.
Biochem/physiol Actions:	Naphthol yellow S (NYS) is used as a stain for protein basic groups. It is an acidic dye and forms a NYS-protein complex at acidic pH. Combination of feulgen and NYS provides DNA to protein ratio.

Symbol	GHS07,GHS08
Signal word	Warning
Hazard statements	H317 - H373
Precautionary statements	P280 - P302 + P352 - P314
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Storage Temp.	room temp
Colour Index Number	10316
UNSPSC	12171500

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