Sodium nucleinate
SIGMA/71790
Synonym: Ribonucleic acid sodium salt
MDL Number: MFCD00148224
Product Type: Chemical
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| form | powder |
| loss | ~5% loss on drying, 20 °C (HV) |
| Quality Level | 100  |
| solubility | H2O: 0.1 g/mL, clear to turbid, brown-yellow (hot) |
| storage temp. | 2-8°C |
| Application: | <ul><BR/><li><strong>Tetrahydropht<WBR>halazine derivative "sodium nucleinate" exert its anti-inflammatory effects through inhibition of oxidative burst in human monocytes:</strong> Describes the anti-inflammatory capabilities of Sodium nucleinate, particularly its ability to inhibit oxidative burst in human monocytes, suggesting its use in anti-inflammatory therapies (<A class="External" onClick="cmCreateManualPageviewTag('pubmed.ncbi.nlm.nih.gov - 71790 SIGMA', 'EXTERNAL LINKS', 'https://pubmed.ncbi.nlm.nih.gov/22856223', window.location);" rel="nofollow" href="https://pubmed.ncbi.nlm.nih.gov/22856223">Jukic et al., 2012</A><img src="/images/pixel.png">).</li><BR/><li><strong>A tetrahydrophthalazine derivative ′sodium nucleinate′ exerts a potent suppressive effect upon LPS-stimulated mononuclear cells in vitro and in vivo:</strong> Outlines the suppressive effects of Sodium nucleinate on LPS-stimulated mononuclear cells, underlining its potential utility in controlling inflammatory responses (<A class="External" onClick="cmCreateManualPageviewTag('pubmed.ncbi.nlm.nih.gov - 71790 SIGMA', 'EXTERNAL LINKS', 'https://pubmed.ncbi.nlm.nih.gov/22397263', window.location);" rel="nofollow" href="https://pubmed.ncbi.nlm.nih.gov/22397263">Jukic et al., 2011</A><img src="/images/pixel.png">).</li><BR/></ul><BR/> |
| Biochem/physiol Actions: | Sodium nucleinate (SN) serves as an immunomodulatory substance, that possess anti-inflammatory effects. |
| General description: | Sodium nucleinate is a derivative of tetrahydrophthalazine. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352106 |