Triclosan
SIGMA/72779 - 97.0-103.0% (active substance, GC)
Synonym: Triclosan; 5-
CAS Number: 3380-34-5
Empirical Formula (Hill Notation): C12H7Cl3O2
Molecular Weight: 289.54
EC Number: 222-182-2
MDL Number: MFCD00800992
Linear Formula: C12H7Cl3O2
Product Type: Chemical
antibiotic activity spectrum | fungi |
assay | 97.0-103.0% (active substance, GC) |
biological source | synthetic |
color | white |
form | powder or crystals |
impurities | ≤0.1% Water (Karl Fischer) |
InChI | 1S/C12H7Cl3O2/c13-7-1-3-1 |
InChI key | XEFQLINVKFYRCS-UHFFFAOYSA |
mode of action | enzyme | inhibits |
mp | 55-59 °C |
Quality Level | 200 |
SMILES string | Oc1cc(Cl)ccc1Oc2ccc(Cl)cc |
solubility | 1 M NaOH: 5% at 25 °C, faintly turbid to clear (colorless solution) |
Application: | A component of cefsulodin-irgasan-novobi |
Biochem/physiol Actions: | It is an inhibitor of the enoyl-ACP (acyl-carrier protein) reductase component of type II fatty acid synthase (FAS-II) in bacteria and Plasmodium. It also inhibits mammalian fatty acid synthase (FASN), and may have anticarcinogenic activity. |
General description: | Chemical structure: diphenyl ether derivative |
Other Notes: | Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place. |
Packaging: | 5, 25 g in poly bottle |
Symbol | GHS07,GHS09 |
Signal word | Warning |
Hazard statements | H315 - H319 - H410 |
Precautionary statements | P264 - P273 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 |
Hazard Codes | Xi,N |
Risk Statements | 36/38-50/53 |
Safety Statements | 26-39-46-60-61 |
RIDADR | UN 3077 9 / PGIII |
WGK Germany | WGK 2 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | 97.0-103.0% (active substance, GC) |
mp | 55-59 °C |
UNSPSC | 51101500 |