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Triclosan

SIGMA/72779 - 97.0-103.0% (active substance, GC)

Synonym: Triclosan; 5-Chloro-2-(2,4-dichlorophenoxy)phenol; Irgasan

CAS Number: 3380-34-5
Empirical Formula (Hill Notation): C12H7Cl3O2
Molecular Weight: 289.54
EC Number: 222-182-2
MDL Number: MFCD00800992
Linear Formula: C12H7Cl3O2
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-72779-5G-F 5 g
$47.50
1/EA
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45-72779-25G-F 25 g
$147.00
1/EA
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antibiotic activity spectrum fungi
assay 97.0-103.0% (active substance, GC)
biological source synthetic
color white
form powder or crystals
impurities ≤0.1% Water (Karl Fischer)
InChI 1S/C12H7Cl3O2/c13-7-1-3-11(9(15)5-7)17-12-4-2-8(14)6-10(12)16/h1-6,16H
InChI key XEFQLINVKFYRCS-UHFFFAOYSA-N
mode of action enzyme | inhibits
mp 55-59 °C
Quality Level 200 
SMILES string Oc1cc(Cl)ccc1Oc2ccc(Cl)cc2Cl
solubility 1 M NaOH: 5% at 25 °C, faintly turbid to clear (colorless solution)
Application: A component of cefsulodin-irgasan-novobiocin selection medium for Yersinia, a human pathogen that may contaminate animal-source food products.
Biochem/physiol Actions: It is an inhibitor of the enoyl-ACP (acyl-carrier protein) reductase component of type II fatty acid synthase (FAS-II) in bacteria and Plasmodium. It also inhibits mammalian fatty acid synthase (FASN), and may have anticarcinogenic activity.
General description: Chemical structure: diphenyl ether derivative
Other Notes: Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.
Packaging: 5, 25 g in poly bottle
Purity 97.0-103.0% (active substance, GC)
mp 55-59 °C
UNSPSC 51101500

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