FITC-CM-Dextran
SIGMA/74817 - average mol wt 150,000
Synonym: FITC-CM-Dextran 150; Fluorescein isothiocyanate–Carboxymethyl–Dextran
Product Type: Chemical
| biological source | synthetic |
| composition | carboxymethyl content, 3-7% |
| conjugate | FITC conjugate |
| extent of labeling | 0.001-0.020 mol FITCmol glucose |
| fluorescence | λex 493 nm; λem 517 nm±5 nm in 0.1 M Tris pH 8.0 |
| form | powder or crystals |
| mol wt | average mol wt 150,000 |
| Quality Level | 100  |
| Application: | FITC-CM-dextran is used to study drug intake and delivery mechanisms in HeLa cell lines. FITC-CM-Dextran was chosen due to its high water solubility and negative charge. It is also a suitable molecule to be used in encapsulation studies for polymersomal drug delivery systems or Ps DDS . FITC-CM-Dextran is a biocompatible molecule used as a starting material in several pharmaceutical and diagnostic applications. |
| General description: | FITC-CM-Dextran, also known as Fluorescein isothiocyanate–Carboxymet FITC-CM-Dextran is manufactured by reacting selected dextran fractions with an activated carboxymethyl derivative in alkali, whereby O-carboxymethyl groups are introduced along the dextran chain. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| UNSPSC | 12352108 |