Azithromycin

SIGMA/75199

Synonym: CP 62,993

CAS Number: 83905-01-5
Empirical Formula (Hill Notation): C₃₈H₇₂N₂O₁₂
Molecular Weight: 748.98
MDL Number: MFCD00873574
Linear Formula: C₃₈H₇₂N₂O₁₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-75199-25MG-F	25 mg	$256.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

antibiotic activity spectrum	viruses
application(s)	environmental
form	powder
InChI	1S/C38H72N2O12/c1-15-27-38(10,46)31(42)24(6)40(13)19-20(2)17-36(8,45)33(52-35-29(41)26(39(11)12)16-21(3)48-35)22(4)30(23(5)34(44)50-27)51-28-18-37(9,47-14)32(43)25(7)49-28/h20-33,35,41-43,45-46H,15-19H2,1-14H3/t20-,21-,22+,23-,24-,25+,26+,27-,28+,29-,30+,31-,32+,33-,35+,36-,37-,38-/m1/s1
InChI key	MQTOSJVFKKJCRP-BICOPXKESA-N
mode of action	protein synthesis \| interferes
optical activity	[α]/D −45±2°, c = 1% in ethanol
Quality Level	200
SMILES string	CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]3O[C@H](C)C[C@@H]([C@H]3O)N(C)C)[C@](C)(O)C[C@@H](C)CN(C)[C@H](C)[C@@H](O)[C@]1(C)O

Application:	Azithromycin has been used: • to treat synchronized Plasmodium falciparum Dd2 parasites for continuous growth assays to study the antiparasitic mechanisms of doxycycline (DOX) • to study its bactericidal activity against Pseudomonas aeruginosa in combination with a recombinant hemolymph plasma lectin (rHPLOE) • in evolution experiments to study P. aeruginosa strain PA14’s response to bacteriostatic antibiotics
Biochem/physiol Actions:	Azithromycin is a broad-spectrum antimicrobial agent, effective against infections associated with respiratory tract, skin, tissues, and genital chlamydia. It acts against Gram-negative bacteria (including Enterobacteriaceae) and several Gram-positive organisms. It also acts against Plasmodium falciparum and P. vivax, which are multidrug resistance species that transmit malaria. Azithromycin targets the plasmodial ribosome and prevents protein synthesis. It is soluble in lipids and metabolizes in the liver by undergoing demethylation. It is commonly used to treat community-acquired pneumonia, sexually transmitted diseases, acute otitis media, and acute exacerbation of chronic obstructive pulmonary disease (COPD).
Features and Benefits:	• Rapidly absorbed • Shows great tissue penetration and procures high intracellular concentration • Distributes widely in body fluids and tissues
General description:	Azithromycin is a hydrophobic azalide and a derivative of erythromycin. It belongs to the macrolide class of antibodies.
Packaging:	Bottomless glass bottle. Contents are inside inserted fused cone.

Symbol	GHS08
Signal word	Danger
Hazard statements	H317 - H334
Precautionary statements	P261 - P280 - P342 + P311
Hazard Codes	Xn
Risk Statements	42/43
Safety Statements	22-36/37-45
RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

UNSPSC

12352200

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