Oligomycin A

SIGMA/75351 - ≥99% (HPLC)

Synonym: MCH 32

CAS Number: 579-13-5
Empirical Formula (Hill Notation): C₄₅H₇₄O₁₁
Molecular Weight: 791.06
EC Number: 209-437-3
MDL Number: MFCD00065705
Linear Formula: C₄₅H₇₄O₁₁
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-75351-5MG	5 mg	$198.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

antibiotic activity spectrum	fungi
assay	≥99% (HPLC)
color	white to off-white
form	powder
InChI	1S/C45H74O11/c1-12-34-17-15-13-14-16-27(4)42(51)44(11,53)43(52)32(9)40(50)31(8)39(49)30(7)38(48)26(3)18-21-37(47)54-41-29(6)35(20-19-34)55-45(33(41)10)23-22-25(2)36(56-45)24-28(5)46/h13-15,17-18,21,25-36,38,40-42,46,48,50-51,53H,12,16,19-20,22-24H2,1-11H3/b14-13+,17-15+,21-18+/t25-,26-,27+,28+,29+,30-,31+,32+,33-,34?,35?,36?,38+,40-,41?,42-,44+,45?/m1/s1
InChI key	MNULEGDCPYONBU-VVXVDZGXSA-N
mode of action	enzyme \| inhibits
Quality Level	200
SMILES string	CCC1CCC2OC3(CC[C@@H](C)C(C[C@H](C)O)O3)[C@H](C)C(OC(=O)C=C[C@@H](C)[C@H](O)[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@H](C)C(=O)[C@@](C)(O)[C@H](O)[C@@H](C)CC=CC=C1)[C@H]2C
solubility	DMSO: soluble
storage temp.	−20°C

Application:	Oligomycin was used to inhibit sucrose synthesis and ¹⁴C translocation in sunflower leaves, to study antibiotic resistance, and to study carotid chemoreceptor responses to O₂ and CO₂ in the cat. Inhibits the growth of Rhodotorula glutinis, Aspergillus niger and other molds.
Biochem/physiol Actions:	Oligomycin blocks oxidative phosphorylation and the electron transport chain by inhibiting membrane bound mitochondrial ATP synthase (ATPase) and proton channel (pump, FO subunit) blocker.
General description:	Chemical structure: macrolide
Other Notes:	Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place. Keep in a dry place.
Packaging:	Bottomless glass bottle. Contents are inside inserted fused cone.

Hazard Codes	Xn
Risk Statements	22
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥99% (HPLC)
Storage Temp.	−20°C
UNSPSC	51101500

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