(4R)-4-Hydroxy-L-glutamic acid

SIGMA/76157 - ≥98.0% (TLC)

Synonym: erythro-(4R)-4-Hydroxy-L-glutamic acid; H-(2S,4R)-γ-Hydroxy-Glu-OH

CAS Number: 2485-33-8
Empirical Formula (Hill Notation): C₅H₉NO₅
Molecular Weight: 163.13
MDL Number: MFCD00672375
Linear Formula: C₅H₉NO₅
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-76157-10MG	10 mg	$243.00 1/EA		Add To Favorites
45-76157-50MG	50 mg	$619.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98.0% (TLC)
color	white
form	powder
InChI	1S/C5H9NO5/c6-2(4(8)9)1-3(7)5(10)11/h2-3,7H,1,6H2,(H,8,9)(H,10,11)/t2-,3+/m0/s1
InChI key	HBDWQSHEVMSFGY-STHAYSLISA-N
mp	171 °C
optical activity	[α]/D 20.5±1.5°, c = 1 in H₂O
Quality Level	100
SMILES string	N[C@@H](C[C@@H](O)C(O)=O)C(O)=O
storage temp.	−20°C

Biochem/physiol Actions:	(4R)-4-Hydroxy-L-glutamic acid or (2S,4R)-4-hydroxyglutamate was shown to activate the metabotropic glutamate receptors, mGlu1a, mGlu2, and mGlu8a in a dose-dependent manner.
Biochem/physiol Actions:	Substrate for aminotransferase; pharmacological characterization at human glutamate transporter subtypes 1-3; for studying structure-activity relationships (SAR) for ionotropic and metabotropic glutamate receptors.
Packaging:	Bottomless glass bottle. Contents are inside inserted fused cone.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98.0% (TLC)
mp	171 °C
Storage Temp.	−20°C
UNSPSC	12352202

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