Paraplast Plus®
SIGMA/76258 - suitable for electron microscopy, pellets (fast-melting)
Synonym: Paraplast Plus® embedding media; Paraffin – polyisobutylene mixture
CAS Number: 125387-89-5
EC Number: 232-315-6
MDL Number: MFCD00131795
Product Type: Chemical
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| application(s) | hematology histology |
| form | pellets (fast-melting) |
| mp | 56-57 °C |
| Quality Level | 100  |
| storage temp. | 2-8°C |
| technique(s) | electron microscopy: suitable |
| thickness | ≤1 μm , short ribbons |
| ≤2 μm , sectioning: continuous ribbons |
| Application: | Paraffin polyisobutylene mixture is a tissue embedding medium composed of highly purified paraffin and polyisobutylene and a low level of dimethyl sulfoxide (DMSO) to enhance the rate of tissue penetration. Paraffin-polyisobutylene (76258) supports thin wrinkle-free sectioning down to 4 microM with more flexible and continuous ribbons. |
| Application: | Recommended for large specimens and tissue that commonly presents infiltration problems. |
| Features and Benefits: | • Produces minimal tissue compression and wrinkle-free sections, and cuts to 4 μm thickness with excellent ribbon continuity. • 0.8% DMSO enhances ease of infiltration and sectioning for tissues difficult to process with regular Paraplast. • Higher melt viscosity and lower permeability to water vapor creates better adhesion and a more pliable, flexible film. • Optimal infiltration and embedding for high-quality sections. • Great compression resistance and ribbon continuity. • Remarkable morphology preservation and distortion-free sections. |
| General description: | Paraplast Plus® is a refined mixture of highly purified paraffin containing complex elastomer of regulated molecular weights plus a small percentage of dimethyl sulfoxide (DMSO) for fast tissue penetration. It produces minimal tissue compression and wrinkle-free sections and cuts to 4 μm thickness with excellent ribbon continuity. Paraplast® tissue embedding media are made from highly purified wax combined with plastic polymers for tensile strength and elasticity. Paraplast Plus® provides rapid infiltration during processing as well as great compression resistance during sectioning for preserved morphology and thin, distortion-free sections. Our range of Paraplast products improve the elasticity of brittle, difficult-to-cut tissues making it easier to produce excellent, wrinkle-free sections. |
| Legal Information: | Paraplast is a registered trademark of Leica Biosystems |
| Legal Information: | Paraplast Plus is a registered trademark of Leica Biosystems |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| mp | 56-57 °C |
| Storage Temp. | 2-8°C |
| UNSPSC | 12171500 |