Synonym: (9Z)-9-Octadecenoic acid (1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester; 1,2-Di(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine; 3-sn-Phosphatidylethanolamine, 1,2-dideoyl; L-β,γ-Dioleoyl-α-cephalin; DOPE; Dioleoyl phosphatidylethanolamine; PE(18:1(9Z)/18:1(9Z))
CAS Number: 4004-05-1
Empirical Formula (Hill Notation): C41H78NO8P
Molecular Weight: 744.03
MDL Number: MFCD00057986
Linear Formula: C41H78NO8P
Product Type: Chemical
assay |
≥97.0% (TLC) |
biological source |
synthetic |
form |
solid |
functional group |
amine |
InChI |
1S/C41H78NO8P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(43)47-37-39(38-49-51(45,46)48-36-35-42)50-41(44)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h17-20,39H,3-16,21-38,42H2,1-2H3,(H,45,46)/b19-17-,20-18- |
InChI key |
MWRBNPKJOOWZPW-CLFAGFIQSA-N |
lipid type |
phosphoglycerides |
Quality Level |
200 |
SMILES string |
CCCCCCCCC=C/CCCCCCCC(=O)OCC(COP(O)(=O)OCCN)OC(=O)CCCCCCCC=C/CCCCCCCC |
storage temp. |
−20°C |
Application: |
1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) forms heterogenous liposomes with N-[1-(2,3-dioleoyloxy)propyl]-N,N,N-trimethylammonium methylsulfate (DOTAP), which are used as delivery vehicles for therapeutic agents . |
Biochem/physiol Actions: |
DOPE in mixed membranes have been found to decrease fluorescence lifetime and increase acyl-chain order. DOPE is an essential component of cationic liposomes designed to deliver DNA into gliosarcoma and kidney cell lines (gene therapy). |
Packaging: |
Bottomless glass bottle. Contents are inside inserted fused cone. |
RIDADR |
NONH for all modes of transport |
WGK Germany |
WGK 3 |
Flash Point(F) |
Not applicable |
Flash Point(C) |
Not applicable |
Purity |
≥97.0% (TLC) |
Storage Temp. |
−20°C |
UNSPSC |
51191904 |