Peptidoglycan from Staphylococcus aureus
SIGMA/77140 - cell wall component
Synonym: Peptidoglycan from S. aureus
MDL Number: MFCD00212486
Product Type: Chemical
form | lyophilized powder |
Quality Level | 100 |
solubility | soluble, hazy to turbid, colorless to faintly yellow |
storage temp. | −20°C |
Application: | Peptidoglycan from Staphylococcus aureus has been used: • for the stimulation of lymphocytes: peptidoglycan activates the toll-like receptor 2 (TLR2), present in mammalian cells. It works as an antagonist of Poly (I:C) • for g-type lysozyme stimulation by intraperitoneally inoculating it into sole specimens • in phosphate buffer saline and injected into Labeo rohita fingerlings, to study its effect on nucleotide-binding oligomerization domain-2 (NOD-2) gene expression |
Biochem/physiol Actions: | The cell wall of gram positive bacteria is largely made up of peptidoglycan. It is composed of polysaccharide chains interlinked by peptide bridges. This peptidoglycan gives a certain rigidity to the cell wall and gives the cell mechanical strength. It is a surface molecule which is known to stimulate immune reactions including cytokine production to fever. |
Other Notes: | Major component of the cell wall in gram positive organisms. Consists of a glycan backbone with alternating β 1-4 linked residues of N-acetyl- |
Packaging: | Bottomless glass bottle. Contents are inside inserted fused cone. |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352201 |