Methoxatin disodium salt

SIGMA/80198 - ≥97.0% (HPLC)

Synonym: PQQ; Pyrrolo-quinoline-quinone disodium salt

CAS Number: 122628-50-6
Empirical Formula (Hill Notation): C₁₄H₄N₂Na₂O₈
Molecular Weight: 374.17
MDL Number: MFCD00151711
Linear Formula: C₁₄H₄N₂Na₂O₈
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-80198-10MG-F	10 mg	$276.00 1/EA		Add To Favorites
45-80198-50MG-F	50 mg	$1130.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥97.0% (HPLC)
biological source	fermentation/recombinant
color	red-brown to deep orange
	red-brown to deep red-brown
form	powder
InChI	1S/C14H6N2O8.2Na/c17-10-4-2-6(14(23)24)15-8(4)7-3(12(19)20)1-5(13(21)22)16-9(7)11(10)18;;/h1-2,15H,(H,19,20)(H,21,22)(H,23,24);;/q;2*+1/p-2
InChI key	UFVBOGYDCJNLPM-UHFFFAOYSA-L
Quality Level	100
SMILES string	OC(=O)c1cc(nc2C(=O)C(=O)c3cc([nH]c3-c12)C(=O)O[Na])C(=O)O[Na]
storage temp.	2-8°C

Application:	Safety assessment of a novel, dietary pyrroloquinoline quinone disodium salt (mnemoPQQ): This study investigates the safety profile of Methoxatin disodium salt, which has implications for its application in assay development for clinical and diagnostic purposes. Specifically, it addresses the compound′s use in dietary supplements and potential crossover into clinical assays where safety and toxicity are paramount (Shiojima et al., 2022 ).
Biochem/physiol Actions:	In bacteria, pyrroloquinoline quinone (PQQ) is used as a redox cycling cofactor. It acts as a cofactor (prosthetic group) for enzyme-catalyzed redox reactions of glucose and methanol dehydrogenase(s). PQQ is used in liposomes to establish a simple homogeneous assay for the detection of membrane permeabilization by antimicrobial peptides and synthetic copolymers. In bovine plasma amine oxidase, methoxatin may acts as the cofactor.
General description:	Methoxatin/pyrroloquinoline quinone (PQQ) is mostly seen in plants, few bacteria and single cell eukaryotes, like yeast. It is mainly obtained from methylotrophic bacteria. PQQ may also present in the tissues of mammals.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥97.0% (HPLC)
Storage Temp.	2-8°C
UNSPSC	12352005

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