Synonym: 1,4-Piperazinediethanesulfonic acid; Piperazine-1,4-bis(2-ethanesulfonic acid); Piperazine-N,N′-bis(2-ethanesulfonic acid)
CAS Number: 5625-37-6
Empirical Formula (Hill Notation): C8H18N2O6S2
Molecular Weight: 302.37
EC Number: 227-057-6
MDL Number: MFCD00006159
Linear Formula: C8H18N2O6S2
Product Type: Chemical
λ |
0.1 M in 1 M NaOH |
anion traces |
chloride (Cl-): ≤200 mg/kg |
|
sulfate (SO42-): ≤50 mg/kg |
assay |
≥99.5% (T) |
cation traces |
Al: ≤5 mg/kg |
|
As: ≤0.1 mg/kg |
|
Ba: ≤5 mg/kg |
|
Bi: ≤5 mg/kg |
|
Ca: ≤10 mg/kg |
|
Cd: ≤5 mg/kg |
|
Co: ≤5 mg/kg |
|
Cr: ≤5 mg/kg |
|
Cu: ≤5 mg/kg |
|
Fe: ≤5 mg/kg |
|
K: ≤50 mg/kg |
|
Li: ≤5 mg/kg |
|
Mg: ≤5 mg/kg |
|
Mn: ≤5 mg/kg |
|
Mo: ≤5 mg/kg |
|
Na: ≤100 mg/kg |
|
Ni: ≤5 mg/kg |
|
Pb: ≤5 mg/kg |
|
Sr: ≤5 mg/kg |
|
Zn: ≤5 mg/kg |
form |
powder |
grade |
for molecular biology |
ign. residue |
≤0.2% (as SO4) |
impurities |
DNases, none detected |
|
insoluble matter, passes filter test |
|
phosphatases, none detected |
|
proteases, none detected |
|
RNases, none detected |
InChI |
1S/C8H18N2O6S2/c11-17(12,13)7-5-9-1-2-10(4-3-9)6-8-18(14,15)16/h1-8H2,(H,11,12,13)(H,14,15,16) |
InChI key |
IHPYMWDTONKSCO-UHFFFAOYSA-N |
loss |
≤0.2% loss on drying, 110 °C |
mp |
>300 °C (lit.) |
pKa (25 °C) |
6.8 |
product line |
BioXtra |
Quality Level |
100 |
SMILES string |
OS(=O)(=O)CCN1CCN(CC1)CCS(O)(=O)=O |
solubility |
0.1 M NaOH: 0.1 M at 20 °C, clear, colorless |
useful pH range |
6.1-7.5 |
UV absorption |
λ: 260 nm Amax: 0.055 |
|
λ: 280 nm Amax: 0.040 |
Application: |
- Sensitive Detection of Immunoglobulin G Stability Using in Real-Time Isothermal Differential Scanning Fluorimetry: Determinants of Protein Stability for Antibody-Based Therapeutics.: The use of PIPES buffer in this study was integral to maintaining the stability of immunoglobulin G during differential scanning fluorimetry. This method is crucial for evaluating the stability of antibody-based therapeutics (Moggridge et al., 2017 ).
|
Other Notes: |
Hybrid selection of mRNA - component of prehybridization buffer |
RIDADR |
NONH for all modes of transport |
WGK Germany |
WGK 3 |
Flash Point(F) |
Not applicable |
Flash Point(C) |
Not applicable |
Purity |
≥99.5% (T) |
mp |
>300 °C (lit.) |
UNSPSC |
12161700 |