Poly(2′-deoxyinosinic-2′-deoxycytidylic acid) sodium salt

SIGMA/81349 - free from low molecular weight nucleotides, lyophilized

Synonym: Poly(dI-dC) sodium salt

CAS Number: 118578-37-3
MDL Number: MFCD00147947
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-81349-500UG	500 µg	$390.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

form	powder
grade	for molecular biology
mol wt	M_r ~2.5 × 10⁶ (broad molecular weight distribution)
	M_r ~2500000
packaging	ampule of ≥10 units A₂₆₀
quality	lyophilized
Quality Level	100
storage temp.	−20°C

Application:	Poly(2′-deoxyinosinic-2′-deoxycytidylic acid) sodium salt has been used in electrophoretic mobility shift assay (EMSA) of the transcription factor AP-2 Alpha (TFAP2A) and in southwestern blotting of human embryonic kidney cells (HEK293) nuclear extract.
Application:	Suitable for • non-specific blocking agent in EMSA • evaluation of DNA methyltransferases • DNA-small molecule or drug interaction studies
Biochem/physiol Actions:	Poly(2′-deoxyinosinic-2′-deoxycytidylic acid), poly(dI-dC) is a synthetic DNA substrate. At high salt, Poly(dI-dC) exists in left handed helical conformation and reverts to right-handed form upon decreasing salt. It is used as a non-specific competitor in electrophoretic mobility shift assay (EMSA).
General description:	Poly (2′-deoxyinosinic-2′-deoxycytidylic acid) sodium salt is an alternating copolymer that acts as a substrate for DNA methyltransferases.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Storage Temp.	−20°C
UNSPSC	12352106

Choose a favorite list for this item:

Catalog Number	Description	Price

		$

Please choose a list :

Continue Shopping

Returns/Order support

Please fill out the form below if you want to request order support from Krackeler Scientific.