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1-Pyrenebutyric hydrazide

SIGMA/82669 - for fluorescence, ≥97.0% (T)

Synonym: 4-(1-Pyrenyl)butyric hydrazide

CAS Number: 55486-13-0
Empirical Formula (Hill Notation): C20H18N2O
Molecular Weight: 302.37
MDL Number: MFCD00467260
Linear Formula: C20H18N2O
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-82669-100MG 100 mg
 $245.00
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assay ≥97.0% (T)
form solid
grade for fluorescence
InChI 1S/C20H18N2O/c21-22-18(23)6-2-3-13-7-8-16-10-9-14-4-1-5-15-11-12-17(13)20(16)19(14)15/h1,4-5,7-12H,2-3,6,21H2,(H,22,23)
InChI key SOPPDVMSOKMZOC-UHFFFAOYSA-N
mp 167-171 °C
Quality Level 100 
SMILES string NNC(=O)CCCc1ccc2ccc3cccc4ccc1c2c34
Application: 1-Pyrenebutyric hydrazide may be used as a fluorescence derivatization reagent in the following:
• Determination of succinylacetone (SA) in urine samples of hepatorenal tyrosinemia patients using high-pressure liquid chromatography with fluorescence detection (HPLC-FLD).
• Determination of glutaric and 3-hydroxyglutaric acids in urine of glutaric acidemia type I patients using HPLC technique with intramolecular excimer-forming fluorescence derivatization.
General description: 1-Pyrenebutyric hydrazide (PBH) finds biological/medical applications in the detection, labeling, and quantification of biological carbonyl compounds including aldehydes and/or ketones and carboxylic acids. It is also industrially used in chemo-sensor materials, lubricants, etc.
Other Notes: Fluorescent labeling reagent for carbonyl compounds, e.g. cyclobutanones formed on food irradiation; Labeling of other compounds
Purity ≥97.0% (T)
mp 167-171 °C
UNSPSC 12352125

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