Aldehyde Dehydrogenase from baker’s yeast
SIGMA/82884 - ≥1 U/mg
CAS Number: 9028-88-0
EC Number: 232-846-3
MDL Number: MFCD00081306
Product Type: Chemical
| form | crystals |
| powder | |
| solid | |
| Quality Level | 100  |
| specific activity | ≥1 U/mg |
| storage temp. | −20°C |
| Application: | Aldehyde dehydrogenase from baker′s yeast has been used to measure the activity of aldehyde dehydrogenase by Tottmar′s method to determine the change in nicotinamide adenine dinucleotide (NADH) levels in serum sample. It has also been used in pyruvate decarboxylase assay. |
| Biochem/physiol Actions: | Aldehyde dehydrogenase (ALDH) is one of the important enzymes involved in the non-P450 aldehyde reduction enzyme system. It protects the cell from the effects of toxic substances. Expression of ALDH is known to increase with the severity of lung cancer. ALDH reduces the extent of cardiac ischemia, arising due to myocardial infarction or post cardiac surgery. Mutation in this gene causes Sjogren‐Larsson syndrome is one such autosomal disorder. |
| Biochem/physiol Actions: | Aldehyde dehydrogenase catalyzes the oxidation of aldehydes into carboxylic acids. |
| General description: | The family of aldehyde dehydrogenase (ALDH) includes 19 genes in human. It is localized to the nucleus, cytosol, mitochondria and endoplasmic reticulum of the cell. |
| Packaging: | Bottomless glass bottle. Contents are inside inserted fused cone. |
| Unit Definition: | 1 U corresponds to the amount of enzyme which oxidizes 1 μmol acetaldehyde (Cat. No. 00070) to acetic acid per minute at pH 8.0 and 25 °C. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| activity | specific activity: ≥1 U/mg |
| Storage Temp. | −20°C |
| UNSPSC | 12352204 |