Pyridoxamine-5′-phosphate
SIGMA/82890 - ≥98.0% (HPLC)
Synonym: 4-
CAS Number: 529-96-4
Empirical Formula (Hill Notation): C8H13N2O5P
Molecular Weight: 248.17
EC Number: 208-471-6
MDL Number: MFCD00023504
Linear Formula: C8H13N2O5P
Product Type: Chemical
| assay | ≥98.0% (HPLC) |
| color | white to light yellow |
| faint beige to light beige | |
| form | powder |
| InChI | 1S/C8H13N2O5P/c1-5-8(11)7 |
| InChI key | ZMJGSOSNSPKHNH-UHFFFAOYSA |
| Quality Level | 100  |
| SMILES string | Cc1ncc(COP(O)(O)=O)c(CN)c |
| technique(s) | HPLC: suitable |
| Application: | Pyridoxamine-5′-phosphate is suitable: • in the enzymatic synthesis of cytidine diphosphate-4-keto-3, 6-dideoxyglucose • as a substrate for pyridoxamine-5′-phosphate phosphatase activity assay • as a substrate to characterize pyridoxine-5′-phosphate oxidase • for the absorbance and fluorescence studies of properties of NaBH4-reduced glycogen phosphorylase b to probe the microenvironment of PMP residue • as a substrate for characterization of pyridoxamine-phosphate transaminase(s) from various species and tissues |
| Biochem/physiol Actions: | pK of pyridoxamine-5′-phosphate (pyridoxamine 5-phosphate, PAMP) in the singlet excited state has been evaluated by absorption and fluorescence spectral studies. |
| Biochem/physiol Actions: | Pyridoxal 5′-phosphate can be converted to pyridoxamine-5′-phosphate in the presence of (S)-α-methylbenzylamine (MBA) as the amine donor by using pyruvate transaminase as a biocatalyst. Pyridoxine 5′-phosphate and pyridoxamine 5′-phosphate are oxidized to pyridoxal 5′-phosphate (PLP) using flavin mononucleotide (FMN) as the immediate electron acceptor and oxygen as the ultimate electron acceptor by the E. coli enzyme pyridoxine (pyridoxamine) 5′-phosphate oxidase. |
| General description: | Pyridoxamine is a derivative of vitamin B6. Pyridoxamine is a water-soluble vitamin. Vitamin B6 derivatives contain a core pyridine ring. Pyridoxaminecontains an amino methyl group at pyridine′s 4′ position. |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315 - H319 - H335 |
| Precautionary statements | P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98.0% (HPLC) |
| UNSPSC | 12352116 |