Saponin

SIGMA/84510 - used as non-ionic surfactant

Synonym: glycosides; saponins

CAS Number: 8047-15-2
EC Number: 232-462-6
MDL Number: MFCD00081981
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-84510-100G	100 g	$105.00 1/EA	Add To Favorites
45-84510-500G	500 g	$491.00 1/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: 84510-100G

12 Principles of Green Chemistry: Principle 7—A raw material or feedstock should be renewable rather than depleting whenever technically and economically practicable.

Properties
Descriptions
Safety Info.
Basic Data

biological source	plant (Quillaya)
CMC	0.001-0.01%
composition	Sapogenin, 8-25%
density	1.015-1.020 g/mL at 20 °C (5% in H₂O)(lit.)
form	powder
greener alternative category	Aligned
greener alternative product characteristics	Less Hazardous Chemical Syntheses Use of Renewable Feedstocks Learn more about the Principles of Green Chemistry .
impurities	10.0-20.0% sulphated ash
InChI	1S/C58H94O27/c1-52(2)29-7-11-55(5)30(8-12-58-31-15-53(3,22-62)13-14-57(31,23-77-58)32(64)16-56(55,58)6)54(29,4)10-9-33(52)82-50-46(85-51-45(40(71)37(68)27(19-61)80-51)84-49-43(74)39(70)36(67)26(18-60)79-49)44(83-48-42(73)38(69)35(66)25(17-59)78-48)28(21-76-50)81-47-41(72)34(65)24(63)20-75-47/h22,24-51,59-61,63-74H,7-21,23H2,1-6H3/t24-,25-,26-,27-,28+,29?,30-,31+,32-,33+,34+,35-,36-,37-,38+,39+,40+,41-,42-,43-,44+,45-,46-,47+,48-,49-,50+,51+,53-,54+,55-,56+,57?,58?/m1/s1
InChI key	MAEBCGDGGATMSC-OSHGGGOQSA-N
Quality Level	300
SMILES string	C[C@]1(CCC23COC4([C@H]2C1)CC[C@@H]5[C@]6(CC[C@@H](C(C6CC[C@]5([C@@]4(C[C@H]3O)C)C)(C)C)O[C@H]7[C@@H]([C@H]([C@H](CO7)O[C@H]8[C@@H]([C@H]([C@@H](CO8)O)O)O)O[C@@H]9[C@@H]([C@H]([C@@H]([C@H](O9)CO)O)O)O)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O[C@@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O)C)C=O
solubility	water: 1 g/10 mL, clear to hazy, yellow to brown
sustainability	Greener Alternative Product
technique(s)	HPLC: suitable
	protein quantification: suitable

Application:	Glycoside used as a nonionic sufactant and adjuvant in vaccine development.
Application:	Saponin has been used: • as a wetting agent to study its effects on the floatability of six plastics • to permeabilize washed neutrophils for immunofluorescence • as a supplement in phosphate buffer saline (PBS) for immunocytochemistry
Biochem/physiol Actions:	Saponins are nonionic surfactant that forms oil-in-water emulsions and acts as a protective colloid. They are used for the direct determination of metals in milk by flame atomic absorption spectrophotometry.
Features and Benefits:	• Suitable for Biochemical and Cell Biology research • Can be used with HPLC and Protein Quantification • High purity product for research applications
General description:	Canonical SMILES: CC1(C2CCC3(C(C2(CCC1OC4C(C(C(CO4)OC5C(C(C(CO5)O)O)O)OC6C(C(C(C(O6)CO)O)O)O)OC7C(C(C(C(O7)CO)O)O)OC8C(C(C(C(O8)CO)O)O)O)C)CCC91C3(CC(C2(C9CC(CC2)(C)C=O)CO1)O)C)C)C
General description:	Saponins, belonging to the class of steroid or triterpenoid glycosides, are widely distributed in plants, marine animals, and certain bacteria, serving as crucial compounds in various research fields, including biochemical, cell biology, and beyond. These amphipathic glycosides exhibit soap-like foaming in aqueous solutions due to their distinctive structure, featuring hydrophilic glycoside moieties combined with a lipophilic triterpene derivative. Beyond their structural uniqueness, saponins play essential roles in biochemical processes, acting as secondary metabolites that facilitate protein penetration through cell membranes. Studies indicate their amphipathic nature and potential as hemolytic agents, contributing to their utility in immunoassays by stimulating the Th1 immune response and cytotoxic T-lymphocyte production. In cell biology, saponins find applications as nonionic surfactants, influencing cellular processes and interactions. Moreover, saponins serve as promising components in vaccine research, functioning as adjuvants that can activate the mammalian immune system. This property, combined with their ability to solubilize low-density lipoproteins and regulate cholesterol concentration in micelles, makes saponins versatile and valuable in multidisciplinary research areas, including biochemical and cell biology research.
General description:	We are committed to bringing you greener alternative products, which adhere to one or more of the 12 Principles of Green Chemistry. This product is Bio-based and thus aligns with ″Use of Renewable Feedstocks″.
Other Notes:	For additional information on our range of Biochemicals , please complete this form .

Symbol	GHS07
Signal word	Warning
Hazard statements	H319 - H335
Precautionary statements	P261 - P264 - P271 - P280 - P304 + P340 + P312 - P305 + P351 + P338
Hazard Codes	Xi
Risk Statements	36/37
Safety Statements	26-37/39
RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Density	1.015-1.020 g/mL at 20 °C (5% in H₂O)(lit.)
UNSPSC	12161900

To Order From a Quote