Spermine tetrahydrochloride
SIGMA/85610 - ≥99.0% (AT), powder or crystals
Synonym: N,N′-Bis(3-aminopropyl)-1,4-butanediamine tetrahydrochloride
CAS Number: 306-67-2
Empirical Formula (Hill Notation): C10H26N4 · 4HCl
Molecular Weight: 348.18
EC Number: 206-189-8
MDL Number: MFCD00012914
Linear Formula: C10H26N4 · 4HCl
Product Type: Chemical
assay | ≥99.0% (AT) |
biological source | microbial |
synthetic | |
form | powder or crystals |
InChI | 1S/C10H26N4.4ClH/c11-5-3- |
InChI key | XLDKUDAXZWHPFH-UHFFFAOYSA |
mp | 310-311 °C (dec.) (lit.) |
Quality Level | 300 |
SMILES string | Cl.Cl.Cl.Cl.NCCCNCCCCNCCC |
solubility | H2O: 0.1 g/mL, clear |
storage temp. | room temp |
Application: | Used to precipitate DNA from low salt aqueous buffers. |
Biochem/physiol Actions: | Mixed NMDA agonist/antagonist at the polyamine site. Neuroprotective effects have been observed at high concentrations (1 mM), while neurotoxicity is observed at lower concentrations. It enhances agonist effectiveness at the strychnine-insensitive glycine site. Plays a role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS). |
Biochem/physiol Actions: | Mixed NMDA agonist/antagonist at the polyamine site. Plays a role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS). |
Symbol | GHS07 |
Signal word | Warning |
Hazard statements | H315 - H319 |
Precautionary statements | P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313 |
Hazard Codes | Xi |
Risk Statements | 36/38 |
Safety Statements | 26-36 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥99.0% (AT) |
mp | 310-311 °C (dec.) (lit.) |
Storage Temp. | room temp |
UNSPSC | 12352200 |