2,5-Dihydroxybenzoic acid
SIGMA/85707 - matrix substance for MALDI-MS, >99.0% (HPLC)
Synonym: 2,5-DHBA; DHB; Gentisic acid; Hydroquinonecarboxylic acid
CAS Number: 490-79-9
Empirical Formula (Hill Notation): C7H6O4
Molecular Weight: 154.12
EC Number: 207-718-5
MDL Number: MFCD00002460
Linear Formula: (HO)2C6H3CO2H
Product Type: Chemical
ε (extinction coefficient) | >2000 at 337 nm |
analyte chemical class(es) | glycans, lipids, organic molecules, peptides, proteins |
analyte functional class(es) | polymers |
assay | >99.0% (HPLC) |
cation traces | Ba: ≤5 mg/kg |
Ca: ≤5 mg/kg | |
Cd: ≤5 mg/kg | |
Co: ≤5 mg/kg | |
Cr: ≤5 mg/kg | |
Cu: ≤5 mg/kg | |
K: ≤5 mg/kg | |
Mg: ≤5 mg/kg | |
Mn: ≤5 mg/kg | |
Na: ≤5 mg/kg | |
Ni: ≤5 mg/kg | |
Pb: ≤5 mg/kg | |
Zn: ≤5 mg/kg | |
form | powder |
grade | matrix substance for MALDI-MS |
InChI | 1S/C7H6O4/c8-4-1-2-6(9)5( |
InChI key | WXTMDXOMEHJXQO-UHFFFAOYSA |
mp | 200-207 °C |
204-208 °C (lit.) | |
Quality Level | 100 |
SMILES string | OC(=O)c1cc(O)ccc1O |
technique(s) | MALDI-MS: suitable |
Application: | 2,5-Dihydroxybenzoic acid is an ionic liquid matrix used for the analysis of biomolecules using matrix-assisted laser desorption/ionization combined with mass spectrometry. |
Application: | Most commonly used matrix for carbohydrates. For MALDI-MS of free neutral glycans. Produces [M+Na]+ ion; may show a weaker [M+K]+ ion. Other species may be generated by the addition of the appropriate inorganic salt. |
Hazard Codes | Xn |
Risk Statements | 22-36/37/38 |
Safety Statements | 26-36 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Purity | >99.0% (HPLC) |
mp | 200-207 °C; 204-208 °C (lit.) |
UNSPSC | 12000000 |