Tetraethylammonium chloride
SIGMA/86614 - BioUltra, for molecular biology, ≥99.0% (AT)
Synonym: Etamon chloride; TEAC; TEA chloride
CAS Number: 56-34-8
Empirical Formula (Hill Notation): C8H20ClN
Molecular Weight: 165.70
EC Number: 200-267-5
MDL Number: MFCD00011828
Linear Formula: (C2H5)4N(Cl)
Product Type: Chemical
λ | 1 M in H2O |
anion traces | bromide (Br-): ≤500 mg/kg |
sulfate (SO42-): ≤50 mg/kg | |
assay | ≥99.0% (AT) |
cation traces | Al: ≤5 mg/kg |
As: ≤0.1 mg/kg | |
Ba: ≤5 mg/kg | |
Bi: ≤5 mg/kg | |
Ca: ≤10 mg/kg | |
Cd: ≤5 mg/kg | |
Co: ≤5 mg/kg | |
Cr: ≤5 mg/kg | |
Cu: ≤5 mg/kg | |
Fe: ≤5 mg/kg | |
K: ≤50 mg/kg | |
Li: ≤5 mg/kg | |
Mg: ≤5 mg/kg | |
Mn: ≤5 mg/kg | |
Mo: ≤5 mg/kg | |
Na: ≤50 mg/kg | |
Ni: ≤5 mg/kg | |
Pb: ≤5 mg/kg | |
Sr: ≤5 mg/kg | |
Zn: ≤5 mg/kg | |
form | powder |
grade | for molecular biology |
impurities | DNases, none detected |
insoluble matter, passes filter test | |
phosphatases, none detected | |
proteases, none detected | |
RNases, none detected | |
InChI | 1S/C8H20N.ClH/c1-5-9(6-2, |
InChI key | YMBCJWGVCUEGHA-UHFFFAOYSA |
mol wt | 165.70 g/mol |
product line | BioUltra |
Quality Level | 100 |
SMILES string | [Cl-].CC[N+](CC)(CC)CC |
solubility | H2O: 1 M at 20 °C, clear, colorless |
technique(s) | gas chromatography (GC): suitable |
UV absorption | λ: 260 nm Amax: 0.03 |
λ: 280 nm Amax: 0.03 |
Application: | Tetraethylammonium chloride has been used: • as a pharmacological agent in electrophysiology to study its pharmacological effects on Cnidarians • as a component in refolding buffer for protein refolding • to puff onto isolated patches to block voltage-gated K+ (Kv3) channels and post-hoc evaluation |
Features and Benefits: | • Assay: ≥99.0% (AT), BioUltra, for molecular biology • Suitable for gas chromatography (GC) |
General description: | Tetraethylammonium (TEA), a simple quaternary ammonium compound, is commonly used to block potassium channels. It can physically enter the pore and block the channel. Additionally, TEA either imitates or antagonizes the actions of choline and acetylcholine, two other quaternary ammonium ions. |
Other Notes: | TEACl method of DNA-DNA hybridization |
Symbol | GHS07 |
Signal word | Warning |
Hazard statements | H315 - H319 |
Precautionary statements | P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313 |
Hazard Codes | Xn |
Risk Statements | 22-36/37/38 |
Safety Statements | 26-36 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | 201.2 °F - closed cup |
Flash Point(C) | 94 °C - closed cup |
Purity | ≥99.0% (AT) |
UNSPSC | 12352107 |