Tetramethylrhodamine ethyl ester perchlorate

SIGMA/87917 - suitable for fluorescence, ≥90% (HPCE)

Synonym: TMRE; TMRE perchlorate; TMRE

CAS Number: 115532-52-0
Empirical Formula (Hill Notation): C₂₆H₂₇ClN₂O₇
Molecular Weight: 514.95
MDL Number: MFCD00467973
Linear Formula: C₂₆H₂₇ClN₂O₇
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-87917-25MG	25 mg	$203.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥90% (HPCE)
fluorescence	λ_ex 540 nm; λ_em 595 nm in DMSO
form	solid
InChI	1S/C26H27N2O3.ClHO4/c1-6-30-26(29)20-10-8-7-9-19(20)25-21-13-11-17(27(2)3)15-23(21)31-24-16-18(28(4)5)12-14-22(24)25;2-1(3,4)5/h7-16H,6H2,1-5H3;(H,2,3,4,5)/q+1;/p-1
InChI key	NBAOBNBFGNQAEJ-UHFFFAOYSA-M
Quality Level	100
SMILES string	[O-]Cl(=O)(=O)=O.CCOC(=O)c1ccccc1-c2c3ccc(cc3[o+]c4cc(ccc24)N(C)C)N(C)C
solubility	alcohols: soluble
	DMSO: soluble
storage temp.	2-8°C
suitability	suitable for fluorescence

Application:	Tetramethylrhodamine ethyl ester perchlorate (TMRE) is used to study the effects of high glucose in inducing mitochondrial morphology and metabolic changes. TMRE perchlorate is also used to study Fullerene C 60 penetration into Leukemic Cells and the subsequent photoinduced Cytotoxic Effects.
General description:	Tetramethylrhodamine ethyl ester perchlorate (TMRE), also known as TMRE perchlorate, is a potential mitochondrial dye. TMRE staining process is reversible, and it doesn’t affect cell proliferation and viability. The sorted cells containing TMRE perchlorate don’t interfere with the subsequent functional assays and hence are a preferred choice for the enrichment of functionally active, unbiased cell populations.
Other Notes:	Potential-sensitive probe for measuring membrane potential changes in mitochondria
Packaging:	Bottomless glass bottle. Contents are inside inserted fused cone.

Symbol	GHS07
Signal word	Warning
Hazard statements	H302 + H332 - H315 - H319
Precautionary statements	P261 - P264 - P301 + P312 - P302 + P352 - P304 + P340 + P312 - P305 + P351 + P338
Hazard Codes	Xn
Risk Statements	20/22-36/38
Safety Statements	26-36
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥90% (HPCE)
Storage Temp.	2-8°C
UNSPSC	12352116

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