Tetrazole solution
SIGMA/88185 - suitable for DNA synthesis, filtered through a 1 μm filter, ~0.45 M in acetonitrile
Synonym: 1H-Tetrazole
CAS Number: 288-94-8
Empirical Formula (Hill Notation): CH2N4
Molecular Weight: 70.05
MDL Number: MFCD00005247
Linear Formula: CH2N4
Product Type: Chemical
| bp | 84 °C (lit.) |
| concentration | ~0.45 M in acetonitrile |
| density | 0.798 g/mL at 20 °C |
| form | liquid |
| impurities | ≤0.003% water |
| InChI | 1S/CH2N4/c1-2-4-5-3-1/h1H |
| InChI key | KJUGUADJHNHALS-UHFFFAOYSA |
| mp | 156-158 °C (lit.) |
| quality | filtered through a 1 μm filter |
| Quality Level | 300  |
| SMILES string | c1nnn[nH]1 |
| technique(s) | DNA synthesis: suitable |
| Application: | Tetrazole solution is useful for DNA synthesis. It may be employed as a catalyst for the in situ synthesis of deoxyribonucleoside phosphoramidites. It may be used in the preparation of following anionic nucleotide-lipids: • thymidine 3′-(1,2-dilauroyl-sn-glycero-3-phosphate) , diC12-3′-dT • thymidine 3′-(1,2-dimyristoyl-sn-glycero-3-phosphate) diC14- 3′-dT • thymidine-3′-(1,2-dipalmitoyl-sn-glycero-3-phosphate) diC16- 3′-dT |
| Disclaimer: | Saturated solution at room temperature; storage below room temperature causes precipitation. |
| General description: | The product is ~0.45M solution of tetrazole in acetonitrile. Tetrazole ring plays significant role in various synthetic and industrial processes. |
| Other Notes: | Catalyst used in the phosphite triester method of oligonucleotide synthesis for the coupling of (dialkylamino)phosphines |
| Packaging: | 100, 500 mL in Sure/Seal™ |
| Symbol |   GHS02,GHS07 |
| Signal word | Danger |
| Hazard statements | H225 - H302 + H312 + H332 - H319 |
| Precautionary statements | P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338 |
| Hazard Codes | F,Xn |
| Risk Statements | 11-20/21/22-36 |
| Safety Statements | 16-26-36/37 |
| RIDADR | UN1993 - class 3 - PG 2 - Tetrazol solution flammable liquids, n |
| WGK Germany | WGK 3 |
| Flash Point(F) | 41.0 °F - closed cup |
| Flash Point(C) | 5 °C - closed cup |
| bp | 84 °C (lit.) |
| mp | 156-158 °C (lit.) |
| Density | 0.798 g/mL at 20 °C |
| UNSPSC | 12352100 |