Nα-Tosyl-L-lysine chloromethyl ketone hydrochloride
SIGMA/90182 - ≥99.0% (AT)
Synonym: (3S)
CAS Number: 4272-74-6
Empirical Formula (Hill Notation): C14H21ClN2O3S · HCl
Molecular Weight: 369.31
EC Number: 224-266-4
MDL Number: MFCD00065395
Linear Formula: C14H21ClN2O3S · HCl
Product Type: Chemical
assay | ≥99.0% (AT) |
biological source | synthetic |
form | powder or crystals |
InChI | 1S/C14H21ClN2O3S.ClH/c1-1 |
InChI key | YFCUZWYIPBUQBD-ZOWNYOTGSA |
optical activity | [α]20/D −7.8±0.5°, c = 2% in H2O |
Quality Level | 100 |
SMILES string | Cl[H].Cc1ccc(cc1)S(=O)(=O |
storage temp. | −20°C |
Other Notes: | An alkylating reagent that may react with histidine or cysteine residues at the active site of enzymes. Inactivates serine proteases such as trypsin and clostripain . Chymotrypsin is not affected. To prevent proteolytic degradation, a combination of TLCK and TPCK can be used throughout the isolation of proteins, as in the isolation of histones. |
Hazard Codes | Xi |
Risk Statements | 36/37/38 |
Safety Statements | 26-36 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥99.0% (AT) |
Storage Temp. | −20°C |
UNSPSC | 12352202 |