Poly(ethylene glycol)

SIGMA/90878 - BioUltra, 300

Synonym: Polyethylene glycol; PEG

CAS Number: 25322-68-3
MDL Number: MFCD00081839
Linear Formula: H(OCH₂CH₂)_nOH
Product Type: Chemical

λ	50 mg/mL in H₂O
anion traces	chloride (Cl^-): ≤50 mg/kg
	sulfate (SO₄^2-): ≤50 mg/kg
cation traces	Al: ≤5 mg/kg
	As: ≤0.1 mg/kg
	Ba: ≤5 mg/kg
	Bi: ≤5 mg/kg
	Ca: ≤10 mg/kg
	Cd: ≤5 mg/kg
	Co: ≤5 mg/kg
	Cr: ≤5 mg/kg
	Cu: ≤5 mg/kg
	Fe: ≤5 mg/kg
	K: ≤200 mg/kg
	Li: ≤5 mg/kg
	Mg: ≤5 mg/kg
	Mn: ≤5 mg/kg
	Mo: ≤5 mg/kg
	Na: ≤200 mg/kg
	Ni: ≤5 mg/kg
	Pb: ≤5 mg/kg
	Sr: ≤5 mg/kg
	Zn: ≤5 mg/kg
density	1.125 g/mL at 20 °C
form	viscous liquid
impurities	insoluble matter:, passes filter test
	≤0.001% peroxides (as H₂O₂):
InChI	1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
InChI key	LYCAIKOWRPUZTN-UHFFFAOYSA-N
mol wt	M_r 285-315
pH	5.5-7.0 (25 °C, 50 mg/mL in H₂O)
product line	BioUltra
Quality Level	100
refractive index	n20/D 1.465
SMILES string	C(CO)O
solubility	H₂O: 50 mg/mL at 25 °C, clear, colorless
UV absorption	λ: 260 nm A_max: 0.06
	λ: 280 nm A_max: 0.03

Application:

Development of Lyophilized Eukaryotic Cell-Free Protein Expression System Based on Leishmania tarentolae.: This study explores the use of Poly(ethylene glycol) (PEG) in creating a lyophilized eukaryotic cell-free protein expression system. The research demonstrates how PEG facilitates the stabilization and preservation of cell-free systems, enhancing protein synthesis capabilities for various biochemical applications (Alfaro-Palma et al., 2024 ).

High-Contrast Luminescent Immunohistochemistry Using PEGylated Lanthanide Complexes.: The application of PEGylated lanthanide complexes in immunohistochemistry significantly improves the contrast and specificity of luminescent signals. This innovation aids in more accurate biochemical analysis and diagnostics (Su et al., 2022 ).

Analyzing Immune Response to Engineered Hydrogels by Hierarchical Clustering of Inflammatory Cell Subsets.: This research investigates the immune responses to PEG-based hydrogels used in tissue engineering. It provides insights into the biocompatibility and inflammatory reactions, essential for designing advanced biomaterials (Fernandez-Yague et al., 2022 ).

Person-Specific Biomolecular Coronas Modulate Nanoparticle Interactions with Immune Cells in Human Blood.: The study shows how PEGylation of nanoparticles affects their interaction with immune cells, influencing drug delivery systems and therapeutic efficacy in biochemistry and molecular biology (Ju et al., 2020 ).

A Post-Insertion Strategy for Surface Functionalization of Bacterial and Mammalian Cell-Derived Extracellular Vesicles.: This paper discusses the post-insertion method using PEG for surface functionalization of extracellular vesicles, enhancing their potential for targeted drug delivery and biochemical research (Jiang et al., 2021 ).

RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point(F)	281.5 °F - closed cup
Flash Point(C)	138.6 °C - closed cup