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Oxyresveratrol

SIGMA/91211 - ≥97.0% (HPLC)

Synonym: (E)-2,3′,4,5′-Stilbenetetrol; 2,3′,4,5′-Tetrahydroxy-trans-stilbene; 4-[(1E)-2-(3,5-Dihydroxyphenyl)ethenyl]-1,3-benzenediol

CAS Number: 29700-22-9
Empirical Formula (Hill Notation): C14H12O4
Molecular Weight: 244.24
MDL Number: MFCD11974969
Linear Formula: C14H12O4
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-91211-100MG 100 mg
$315.00
1/EA
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45-91211-500MG 500 mg
$1200.00
1/EA
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application(s) metabolomics
vitamins, nutraceuticals, and natural products
assay ≥97.0% (HPLC)
form solid
InChI 1S/C14H12O4/c15-11-4-3-10(14(18)8-11)2-1-9-5-12(16)7-13(17)6-9/h1-8,15-18H/b2-1+
InChI key PDHAOJSHSJQANO-OWOJBTEDSA-N
Quality Level 100 
SMILES string Oc1ccc(C=Cc2cc(O)cc(O)c2)c(O)c1
Application: Oxyresveratrol has been used:
• with poly(lactic-co-glycolic acid) (PLGA) nanoparticles to test its antioxidant effects and to investigate its role in the inhibition of superoxide anion (O2-) generation
• to test its effects as an anti-neuroinflammatory agent on interleukin-1 beta (IL-1β)-induced HMC3 human microglial cell line
• as a reference standard to determine its existence in Artocarpus lakoocha Roxb. (AL) extract using high-performance liquid chromatography (HPLC)

Biochem/physiol Actions: Oxyresveratrol is well-known due to its diverse biological and pharmacological properties. It is a potent antioxidant and anti-inflammatory agent. ORV also exerts neuroprotective activities and protects against cerebral ischemia, stroke, and several neurodegenerative disorders. It also displays anti-cancer, antimicrobial, hepatoprotective properties and protects against several other metabolic disorders. It is also a potent tyrosinase inhibitor.
General description: Oxyresveratrol (OXY or ORV) is a naturally occurring polyphenolic stilbene that is predominantly present in the heartwood of many plants. It is primarily extracted from Artocarpus lakoocha Roxb. plant, and is one of the main constituents of this plant. ORV has a very simple chemical structure with a trans-1,2-diphenylethylene in its core and two hydroxyls (OH) groups attached to each aromatic ring.
Packaging: Bottomless glass bottle. Contents are inside inserted fused cone.
Purity ≥97.0% (HPLC)
UNSPSC 12352200

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