Triton™ X-114
SIGMA/93422
Synonym: (1,1,3,3-
CAS Number: 9036-19-5
MDL Number: MFCD00128254
Linear Formula: (C2H4O)n C14H22O, n = 7 or 8
Product Type: Chemical
anion traces | chloride (Cl-): ≤50 mg/kg |
sulfate (SO42-): ≤50 mg/kg | |
cation traces | Ca: ≤10 mg/kg |
Cd: ≤5 mg/kg | |
Co: ≤5 mg/kg | |
Cr: ≤5 mg/kg | |
Cu: ≤5 mg/kg | |
Fe: ≤15 mg/kg | |
K: ≤500 mg/kg | |
Mg: ≤5 mg/kg | |
Mn: ≤5 mg/kg | |
Na: ≤500 mg/kg | |
Ni: ≤5 mg/kg | |
Pb: ≤5 mg/kg | |
Zn: ≤5 mg/kg | |
CMC | 0.2 mM (20-25°C) |
density | 1.052 g/mL at 20 °C |
1.058 g/mL at 25 °C (lit.) | |
description | non-ionic |
form | liquid |
HLB | 12.4 |
ign. residue | ≤0.2% |
impurities | ≤0.001% peroxides (as H2O2) |
≤1% water | |
InChI | 1S/C28H50O8/c1-27(2,3)24- |
InChI key | HNLXNOZHXNSSPN-UHFFFAOYSA |
mol wt | average mol wt 537 |
Quality Level | 200 |
refractive index | n |
n |
|
SMILES string | CC(C)(C)CC(C)(C)c1ccc(OCC |
transition temp | cloud point 23 °C |
pour point ~−9 °C |
Application: | Triton™ X-114 has been used: • In phase separation of integral membrane proteins • In the purification of bacterial inclusion bodies • To study the clouding phenomenon in promethazine hydrochloride, an amphiphilic phenothiazine drug • To partition conditioned media into insoluble and soluble phases before Western blotting • For solubilization of phosphatidylinositol 4-phosphate 5-kinase from bovine brain |
General description: | Triton™ X-114 is a nonionic detergent. It is a good detergent for solubilizing membranes having reversible phase-separation property useful for the separation of intrinsic membrane proteins. Solution of Triton™ X-114 is homogeneous at 0°C but phase separation into aqueous phase and a detergent phase occurs above 20°C. Phase separation of proteins in solutions of Triton™ X-114 has been investigated. This octylphenol ethoxylate is compatible with anionic, cationic, and other nonionic surfactants and chemically stable in most acidic & alkaline solutions. |
Legal Information: | Triton is a trademark of The Dow Chemical Company or an affiliated company of Dow |
Packaging: | 1 L in glass bottle |
Packaging: | 250 mL in glass bottle |
Symbol | GHS05,GHS07,GHS09 |
Signal word | Danger |
Hazard statements | H302 - H315 - H318 - H410 |
Precautionary statements | P264 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338 |
Hazard Codes | Xn,N |
Risk Statements | 22-41-51/53 |
Safety Statements | 26-39-61 |
RIDADR | UN 3082 9 / PGIII |
WGK Germany | WGK 3 |
Flash Point(F) | 483.8 °F |
Flash Point(C) | 251 °C |
Density | 1.052 g/mL at 20 °C; 1.058 g/mL at 25 °C (lit.) |
Refractive Index | n |
UNSPSC | 12161900 |