L-Tryptophan
SIGMA/93659 - BioUltra, ≥99.5% (NT)
Synonym: (S)
CAS Number: 73-22-3
Empirical Formula (Hill Notation): C11H12N2O2
Molecular Weight: 204.23
EC Number: 200-795-6
MDL Number: MFCD00064340
Linear Formula: C11H12N2O2
Product Type: Chemical
| absorption | cut-off at 326 nm in 0.5 M HCl at 0.5 M |
| anion traces | chloride (Cl-): ≤50 mg/kg |
| sulfate (SO42-): ≤50 mg/kg | |
| application(s) | cell analysis |
| assay | ≥99.5% (NT) |
| cation traces | Al: ≤5 mg/kg |
| As: ≤0.1 mg/kg | |
| Ba: ≤5 mg/kg | |
| Bi: ≤5 mg/kg | |
| Ca: ≤10 mg/kg | |
| Cd: ≤5 mg/kg | |
| Co: ≤5 mg/kg | |
| Cr: ≤5 mg/kg | |
| Cu: ≤5 mg/kg | |
| Fe: ≤5 mg/kg | |
| K: ≤50 mg/kg | |
| Li: ≤5 mg/kg | |
| Mg: ≤5 mg/kg | |
| Mn: ≤5 mg/kg | |
| Mo: ≤5 mg/kg | |
| Na: ≤50 mg/kg | |
| Ni: ≤5 mg/kg | |
| Pb: ≤5 mg/kg | |
| Sr: ≤5 mg/kg | |
| Zn: ≤5 mg/kg | |
| color | white |
| form | powder or crystals |
| ign. residue | ≤0.1% |
| impurities | insoluble matter, passes filter test |
| InChI | 1S/C11H12N2O2/c12-9(11(14 |
| InChI key | QIVBCDIJIAJPQS-VIFPVBQESA |
| loss | ≤0.1% loss on drying, 20 °C (HV) |
| mp | 280-285 °C (dec.) (lit.) |
| optical activity | [α]20/D −31.5±1°, c = 1% in H2O |
| product line | BioUltra |
| Quality Level | 100  |
| SMILES string | N[C@@H](Cc1c[nH]c2ccccc12 |
| solubility | 0.5 M HCl: 0.1 g/mL at 20 °C, clear, colorless to faintly yellow |
| Application: | L-Tryptophan has been used as a nutritional supplement to study its effect on the circadian clock of primary cell lines. It has also been used as a test amino acid aerosol to study the variation in the fluorescence intensity of thermally-exposed bacterial bioaerosols. |
| Biochem/physiol Actions: | Tryptophan (Trp) is one of the functional amino acids that are associated with growth, reproduction, maintenance and immunity. Increased Trp availability is necessary for the regulation of mood, cognition and behaviour. It is hypothesised that L-Trp might be useful in inducing sleep in healthy adults against the normal circadian rhythm. Trp uptake by the brain depends on the plasma ratio of Trp to all of the other LNAAs (large neutral amino acids). Higher the Trp:LNAAs ratio, greater is the Trp uptake. |
| Legal Information: | Sephadex is a registered trademark of Cytiva |
| Legal Information: | Sepharose is a trademark of Cytiva |
| Other Notes: | Amino acid precursor of serotonin and melatonin |
| Other Notes: | In tryptophan-substituted Sephadex® and Sepharose™ for the improved chromatographic separation of cellulases; As spacer in isotachophoresis of serum proteins; Growth requirement of various microorganisms. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥99.5% (NT) |
| mp | 280-285 °C (dec.) (lit.) |
| UNSPSC | 12352209 |