LL-37 (human) trifluoroacetate salt
SIGMA/94261 - ≥95% (HPLC)
Synonym: Human LL-37 amide Trifluoroacetate
Empirical Formula (Hill Notation): C205H341N61O52 · xC2HF3O2
Molecular Weight: 4492.28 (free base basis)
Linear Formula: C205H341N61O52 · xC2HF3O2
Product Type: Chemical
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| antibiotic activity spectrum | Gram-negative bacteria |
| Gram-positive bacteria | |
| viruses | |
| assay | ≥95% (HPLC) |
| color | colorless to white |
| form | powder (Lyophilisate) |
| mode of action | cell membrane | interferes |
| Quality Level | 200  |
| solubility | H2O: 1 mg/mL, clear, colorless |
| storage temp. | −20°C |
| Amino Acid Sequence: | Leu-Leu-Gly-Asp-Phe-Phe-A |
| Application: | LL-37 is used to study host defense mechanisms. |
| Biochem/physiol Actions: | LL-37 is a muntifunctional host defense peptide with antibacterial, antiviral, and immunomodulating activities. It is the only cathelicidin-type peptide found in human. In addition to its antimicrobial activities, LL-37 has been found to regulate inflammation and neutralize lipopolysaccharides from Gram-negative bacteria. |
| General description: | Chemical structure: peptide |
| Other Notes: | Keep container tightly closed in a dry and well-ventilated place. Store under inert gas. Keep in a dry place. |
| Packaging: | 1mg |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% (HPLC) |
| Storage Temp. | −20°C |
| UNSPSC | 51101500 |