LL-37 (human) trifluoroacetate salt
SIGMA/94261 - ≥95% (HPLC)
Synonym: Human LL-37 amide Trifluoroacetate
Empirical Formula (Hill Notation): C205H341N61O52 · xC2HF3O2
Molecular Weight: 4492.28 (free base basis)
Linear Formula: C205H341N61O52 · xC2HF3O2
Product Type: Chemical
antibiotic activity spectrum | Gram-negative bacteria |
Gram-positive bacteria | |
viruses | |
assay | ≥95% (HPLC) |
color | colorless to white |
form | powder (Lyophilisate) |
mode of action | cell membrane | interferes |
Quality Level | 200 |
solubility | H2O: 1 mg/mL, clear, colorless |
storage temp. | −20°C |
Amino Acid Sequence: | Leu-Leu-Gly-Asp-Phe-Phe-A |
Application: | LL-37 is used to study host defense mechanisms. |
Biochem/physiol Actions: | LL-37 is a muntifunctional host defense peptide with antibacterial, antiviral, and immunomodulating activities. It is the only cathelicidin-type peptide found in human. In addition to its antimicrobial activities, LL-37 has been found to regulate inflammation and neutralize lipopolysaccharides from Gram-negative bacteria. |
General description: | Chemical structure: peptide |
Other Notes: | Keep container tightly closed in a dry and well-ventilated place. Store under inert gas. Keep in a dry place. |
Packaging: | 1mg |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥95% (HPLC) |
Storage Temp. | −20°C |
UNSPSC | 51101500 |