Vancomycin hydrochloride from Streptomyces orientalis
SIGMA/94747 - ≥85% (Vancomycin B)
Synonym: Vancomycin HCL
CAS Number: 1404-93-9
Empirical Formula (Hill Notation): C66H75Cl2N9O24 · HCl
Molecular Weight: 1485.71
Linear Formula: C66H75Cl2N9O24 · HCl
Product Type: Chemical
antibiotic activity spectrum | Gram-positive bacteria |
assay | ≥85% (Vancomycin B) |
biological source | Streptomyces orientalis |
color | , off-white to brown or White to orange-brown |
form | powder |
InChI | 1S/C66H75Cl2N9O24.ClH/c1- |
InChI key | LCTORFDMHNKUSG-XTTLPDOESA |
mode of action | cell wall synthesis | interferes |
Quality Level | 100 |
SMILES string | Cl[H].CO[C@@H]1O[C@H](CO) |
storage temp. | 2-8°C |
Application: | Vancomycin has been used to study transcriptional induction of the penicillin-binding protein 2 gene in Staphylococcus aureus, the correlation of vancomycin and daptomycin susceptibility in Staphylococcus aureus, and the evaluation of telavancin activity in Staphylococcus aureus. |
Biochem/physiol Actions: | Mode of action: Inhibits incorporation of terminal D-alanyl-D-alanine moieties of the NAM/NAG-peptides. Antimicrobial Spectrum: Active against Gram-positive bacteria |
General description: | Chemical structure: glycopeptide |
Other Notes: | Keep container tightly closed in a dry and well-ventilated place. Handle and store under inert gas. |
Packaging: | 250mg, 1g, 5g |
Symbol | GHS08 |
Signal word | Danger |
Hazard statements | H317 - H334 |
Precautionary statements | P261 - P280 - P284 - P304 + P340 - P342 + P311 |
Hazard Codes | Xi |
Risk Statements | 43 |
Safety Statements | 36/37 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 2 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥85% (Vancomycin B) |
Storage Temp. | 2-8°C |
UNSPSC | 51101500 |