Vancomycin hydrochloride from Streptomyces orientalis

SIGMA/94747 - ≥85% (Vancomycin B)

Synonym: Vancomycin HCL

CAS Number: 1404-93-9
Empirical Formula (Hill Notation): C₆₆H₇₅Cl₂N₉O₂₄ · HCl
Molecular Weight: 1485.71
MDL Number: MFCD00064593
Linear Formula: C₆₆H₇₅Cl₂N₉O₂₄ · HCl
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-94747-250MG	250 mg	$87.50 1/EA		Add To Favorites
45-94747-1G	1 g	$189.00 1/EA		Add To Favorites
45-94747-5G	5 g	$746.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

antibiotic activity spectrum	Gram-positive bacteria
assay	≥85% (Vancomycin B)
biological source	Streptomyces orientalis
color	, off-white to brown or White to orange-brown
form	powder
InChI	1S/C66H75Cl2N9O24.ClH/c1-23(2)12-34(71-5)58(88)76-49-51(83)26-7-10-38(32(67)14-26)97-40-16-28-17-41(55(40)101-65-56(54(86)53(85)42(22-78)99-65)100-44-21-66(4,70)57(87)24(3)96-44)98-39-11-8-27(15-33(39)68)52(84)50-63(93)75-48(64(94)95)31-18-29(79)19-37(81)45(31)30-13-25(6-9-36(30)80)46(60(90)77-50)74-61(91)47(28)73-59(89)35(20-43(69)82)72-62(49)92;/h6-11,13-19,23-24,34-35,42,44,46-54,56-57,65,71,78-81,83-87H,12,20-22,70H2,1-5H3,(H2,69,82)(H,72,92)(H,73,89)(H,74,91)(H,75,93)(H,76,88)(H,77,90)(H,94,95);1H/t24-,34+,35-,42+,44-,46+,47+,48-,49+,50-,51+,52+,53+,54-,56+,57+,65-,66-;/m0./s1
InChI key	LCTORFDMHNKUSG-XTTLPDOESA-N
mode of action	cell wall synthesis \| interferes
Quality Level	100
SMILES string	Cl[H].CO[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O[C@H]2C[C@](C)(N)[C@@H](O)[C@@H](C)O2.CN[C@H](CC(C)C)C(=O)NC3[C@H](O)c4ccc(Oc5cc6Oc7ccc(cc7Cl)[C@@H](O)[C@H]8NC(=O)[C@H](NC(=O)[C@H](NC(=O)[C@H](CC(N)=O)NC3=O)c(c5)c6)c9ccc(O)c(c9)-c%10c(O)cc(O)cc%10[C@@H](NC8=O)C(O)=O)c(Cl)c4
storage temp.	2-8°C

Application:	Vancomycin has been used to study transcriptional induction of the penicillin-binding protein 2 gene in Staphylococcus aureus, the correlation of vancomycin and daptomycin susceptibility in Staphylococcus aureus, and the evaluation of telavancin activity in Staphylococcus aureus.
Biochem/physiol Actions:	Mode of action: Inhibits incorporation of terminal D-alanyl-D-alanine moieties of the NAM/NAG-peptides. Antimicrobial Spectrum: Active against Gram-positive bacteria
General description:	Chemical structure: glycopeptide
Other Notes:	Keep container tightly closed in a dry and well-ventilated place. Handle and store under inert gas.
Packaging:	250mg, 1g, 5g

Symbol	GHS08
Signal word	Danger
Hazard statements	H317 - H334
Precautionary statements	P261 - P280 - P284 - P304 + P340 - P342 + P311
Hazard Codes	Xi
Risk Statements	43
Safety Statements	36/37
RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥85% (Vancomycin B)
Storage Temp.	2-8°C
UNSPSC	51282703

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