Retinol
SIGMA/95144 - BioXtra, ≥97.5% (HPLC), ~3100 U/mg
Synonym: Axerophthol; Vitamin A; Vitamin A alcohol; Vitamin A1; all-trans-
CAS Number: 68-26-8
Empirical Formula (Hill Notation): C20H30O
Molecular Weight: 286.45
EC Number: 200-683-7
MDL Number: MFCD00001552
Linear Formula: C20H30O
Product Type: Chemical
assay | ≥97.5% (HPLC) |
biological source | synthetic |
color | faint yellow to very dark yellow |
form | (Powder or Powder with Lumps) |
InChI | 1S/C20H30O/c1-16(8-6-9-17 |
InChI key | FPIPGXGPPPQFEQ-OVSJKPMPSA |
mp | 56-61 °C |
61-63 °C (lit.) | |
product line | BioXtra |
Quality Level | 200 |
shelf life | limited shelf life |
shipped in | dry ice |
SMILES string | CC1(C)C(/C=C/C(C)=C/C=C/C |
specific activity | ~3100 U/mg |
storage temp. | −20°C |
Application: | Retinol has been used: • as a standard in peak identification and quantification in reverse phase HPLC • as a standard to estimate the concentration of vitamin A • to study the inhibitory effect of retinol on murine norovirus (MNV) replication in murine RAW 264.7 cells • as a component in the reaction mixture for the lecithin:retinol acyltransferase (LRAT) assay |
Biochem/physiol Actions: | It is not biologically active and works as a precursor of active retinoids. Retinol is converted to retinaldehyde and subsequently to retinoic acid. |
Biochem/physiol Actions: | Retinal, retinol and retinoic acid are the aldehyde, alcohol and acid forms of vitamin A. The retinoids exist as many geometric isomers due to the unsaturated bonds in the aliphatic chain. Retinol is biological active in a wide range of processes. |
General description: | Retinol or vitamin A alcohol is the main circulating form of vitamin A. |
Packaging: | Bottomless glass bottle. Contents are inside inserted fused cone. |
Unit Definition: | 1 U corresponds to 1 international U acc. to Ph Eur II, 217 (1983) |
Symbol | GHS07,GHS08 |
Signal word | Danger |
Hazard statements | H317 - H319 - H360FD - H413 |
Precautionary statements | P201 - P273 - P280 - P302 + P352 - P305 + P351 + P338 - P308 + P313 |
Hazard Codes | Xn |
Risk Statements | 22-38 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 1 |
Purity | ≥97.5% (HPLC) |
activity | specific activity: ~3100 U/mg |
mp | 56-61 °C; 61-63 °C (lit.) |
Storage Temp. | −20°C |
UNSPSC | 12352205 |