(S)-AMPA
SIGMA/A0326 - ≥97%
Synonym: (S)-α-Amino-3-hydroxy-5-methylisoxazole-4-propionic acid
CAS Number: 83643-88-3
Empirical Formula (Hill Notation): C7H10N2O4
Molecular Weight: 186.17
MDL Number: MFCD00672630
Linear Formula: C7H10N2O4
Product Type: Chemical
| assay | ≥97% |
| form | powder |
| InChI | 1S/C7H10N2O4/c1-3-4(6(10) |
| InChI key | UUDAMDVQRQNNHZ-YFKPBYRVSA |
| Quality Level | 100  |
| SMILES string | Cc1onc(O)c1C[C@H](N)C(O)= |
| Application: | (S)-AMPA has also been used to activate rostromedial tegmental nucleus (RMTg), to study aversive conditioning in relation with cocaine-induced avoidance behaviors in mice. |
| Application: | (S)-AMPA has been used to selectively eliminate the neural cochlear component of adult barn owls by destroying afferent synapses. |
| Biochem/physiol Actions: | Active enantiomer of (RS)-AMPA zwitterion. Potent agonist at the AMPA subclass of ionotropic glutamate receptors. |
| Biochem/physiol Actions: | Potent agonist at the AMPA subclass of ionotropic glutamate receptors; active enantiomer. |
| Features and Benefits: | This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm . |
| Features and Benefits: | This compound is featured on the Glutamate Receptors (Ion Channel Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
| General description: | AMPA (α-amino-3-hydroxy-5-meth |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥97% |
| UNSPSC | 12352200 |